Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7799823 | 1.00 | TSHR (0.50) | TSHREPHX2SHBGALDH1A1ESR2 | |
| SCHEMBL219048 | 1.00 | TSHR (0.50) | TSHREPHX2SHBGALDH1A1ESR2 | |
| SCHEMBL7077398 | 1.00 | TSHR (0.50) | TSHREPHX2SHBGALDH1A1ESR2 | |
| SCHEMBL2450232 | 0.89 | TSHR (0.60) | TSHREPHX2SHBGALDH1A1ESR2 | |
| SCHEMBL12876612 | 0.89 | TSHR (0.60) | TSHREPHX2SHBGALDH1A1ESR2 | |
| SCHEMBL14159019 | 0.89 | TSHR (0.41) | TSHREPHX2SHBG | |
| SCHEMBL787666 | 0.86 | TSHR (0.56) | TSHREPHX2SHBGALDH1A1 | |
| SCHEMBL12428113 | 0.86 | TSHR (0.56) | TSHREPHX2SHBGALDH1A1 | |
| SCHEMBL9396681 | 0.86 | TSHR (0.56) | TSHREPHX2SHBGALDH1A1 | |
| SCHEMBL17070218 | 0.86 | TSHR (0.56) | TSHREPHX2SHBGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60019749-A | — | — | None | — | — | JP | disclosed |
| US-4631328-A | LIQUID CRYSTALS | BASF AKTIENGESELLSCHAFT (DE) | 1986-12-23 | — | — | US | disclosed |
| EP-0090282-B1 | POLYMERS HAVING MESOGEN GROUPS AND COLOURING MATTER IN THE SIDE CHAIN | BASF Aktiengesellschaft (DE) | 1986-02-05 | — | — | EP | disclosed |
| JP-S6019749-A | ESTER DERIVATIVE OF TRANS,TRANS-BICYCLOHEXANE-4,4'-DIOL | CHISSO CORP | 1985-01-31 | — | — | JP | disclosed |
| EP-0090282-A1 | Polymers having mesogen groups and colouring matter in the side chain | BASF Aktiengesellschaft (DE) | 1983-10-05 | — | — | EP | disclosed |