Sugi Predict

Sugi Predict / Compounds / SCHEMBL787666

SCHEMBL787666

SCHEMBL787666

OC1CCC(C2CCCCC2)CC1

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 1/20 0.56
▸ ALDH1A1 P00352 1/20 0.53
▸ SLC18A3 Q16572 2/20 0.41
▸ HSD11B1 P28845 2/20 0.32
▸ EPHX2 P34913 1/20 0.32
▸ CES2 O00748 1/20 0.32
▸ CES1 P23141 1/20 0.32
▸ SHBG P04278 1/20 0.31
▸ CA1 P00915 1/20 0.30
▸ CA2 P00918 1/20 0.30
▸ CA4 P22748 1/20 0.30
▸ PKM P14618 1/20 0.30
▸ HSD11B2 P80365 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17070218 1.00 TSHR (0.56) TSHRALDH1A1SLC18A3HSD11B1EPHX2
SCHEMBL9396681 1.00 TSHR (0.56) TSHRALDH1A1SLC18A3HSD11B1EPHX2
SCHEMBL12428113 1.00 TSHR (0.56) TSHRALDH1A1SLC18A3HSD11B1EPHX2
SCHEMBL2450232 0.97 TSHR (0.60) TSHRALDH1A1SLC18A3EPHX2SHBG
SCHEMBL12876612 0.97 TSHR (0.60) TSHRALDH1A1SLC18A3EPHX2SHBG
Biphenyl SCHEMBL6720507 0.90 TSHR (0.71) TSHRALDH1A1SLC18A3HSD11B1CES2
SCHEMBL7077398 0.86 TSHR (0.50) TSHRALDH1A1EPHX2SHBG
SCHEMBL219048 0.86 TSHR (0.50) TSHRALDH1A1EPHX2SHBG
SCHEMBL7799823 0.86 TSHR (0.50) TSHRALDH1A1EPHX2SHBG
SCHEMBL10879751 0.86 TSHR (0.50) TSHRALDH1A1EPHX2SHBG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 417 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260098118-A1 Non-Softening Thermoplastic Polyurethanes LUBRIZOL ADVANCED MATERIALS, INC. (US) 2026-04-09 — — US claimed
EP-4590733-A1 NON-SOFTENING THERMOPLASTIC POLYURETHANES Lubrizol Advanced Materials, Inc. (US) 2025-07-30 — — EP claimed
US-20250170530-A1 METHOD FOR PREPARING LOOSE CROSS-SECTIONAL ASYMMETRIC ISOPOROUS MEMBRANE BASED ON THERMALLY INDUCED PHASE SEPARATION PROCESS ZHEJIANG UNIVERSITY OF TECHNOLOGY (CN) 2025-05-29 — — US claimed
WO-2024064070-A1 NON-SOFTENING THERMOPLASTIC POLYURETHANES LUBRIZOL ADVANCED MATERIALS, INC. (US) 2024-03-28 — — WO claimed
US-20180042862-A1 ANTIOXIDANT DIETARY SUPPLEMENT COMPOSITIONS AND METHODS FOR MAINTAINING HEALTHY SKIN CHOMCZYNSKI PIOTR (US) 2018-02-15 — — US claimed
EP-1817017-B1 ANTIOXIDANT DIETARY SUPPLEMENT COMPOSITIONS AND METHODS FOR MAINTAINING HEALTHY SKIN CHOMCZYNSKI PIOTR (US) 2017-05-31 — — EP claimed
CN-106045802-A Preparation method of alicyclic and aromatic-aliphatic chloroformate 长江大学 2016-10-26 — — CN claimed
US-9206099-B2 Method for producing hydrogenated biphenol DAICEL CORPORATION (JP) 2015-12-08 — — US claimed
US-9162950-B2 — — 2015-10-20 — — US claimed
US-20150250911-A1 MALODOR COUNTERACTING COMPOSITIONS Givaudan, S.A. (CH) 2015-09-10 — — US claimed
EP-1781236-A1 COSMETIC COMPOSITIONS COMPRISING SPECIFIC CYCLOHEXANMONO-, -DI- OR -TRIOLS OR CYCLOHEXYL METHAN- OR -ETHAN- OR -PROPOANOLS Molecular Research Center, Inc. (US) 2007-05-09 — — EP claimed
EP-1515710-B1 METHOD OF TREATING ROSACEA BY TOPICAL APPLICATION OF A CYCLOHEXANE DERIVATIVE CHOMCZYNSKI PIOTR (US) 2007-03-21 — — EP claimed
WO-2006060470-A1 ANTIOXIDANT DIETARY SUPPLEMENT COMPOSITIONS AND METHODS FOR MAINTAINING HEALTHY SKIN CHOMCZYNSKI PIOTR (US) 2006-06-08 — — WO claimed
US-20060121133-A1 Antioxidant dietary supplement compositions and methods for maintaining healthy skin CHOMCZYNSKI PIOTR 2006-06-08 — — US claimed
WO-2006026006-A1 COSMETIC COMPOSITIONS COMPRISING SPECIFIC CYCLOHEXANMONO-, -DI- OR -TRIOLS OR CYCLOHEXYL METHAN- OR -ETHAN- OR -PROPOANOLS MOLECULAR RESEARCH CENTER, INC. (US) 2006-03-09 — — WO claimed
US-20060045892-A1 Cosmetic compositions MOLECULAR RESEARCH CENTER, INC. 2006-03-02 — — US claimed
EP-1515710-A1 METHOD OF TREATING ROSACEA BY TOPICAL APPLICATION OF A CYCLOHEXANE DERIVATIVE Chomczynski, Piotr (US) 2005-03-23 — — EP claimed
US-6723755-B2 TOPICALLY APPLYING SAFE AND EFFECTIVE AMOUNT OF CYCLOHEXANOL AND/OR DERIVATIVES CHOMCZYNSKI PIOTR (US) 2004-04-20 — — US claimed
WO-2003105816-A1 METHOD OF TREATING ROSACEA BY TOPICAL APPLICATION OF A CYCLOHEXANE DERIVATIVE CHOMCZYNSKI PIOTR (US) 2003-12-24 — — WO claimed
US-20030232893-A1 Method of treating rosacea CHOMCZYNSKI PIOTR (US) 2003-12-18 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150250911-A1 MALODOR COUNTERACTING COMPOSITIONS C3AR1, OR10J3, C5 TSHR 2332/4885ALDH1A1 333/4885SLC18A3 597/4885
US-20180042862-A1 ANTIOXIDANT DIETARY SUPPLEMENT COMPOSITIONS AND METHODS FOR MAINTAINING HEALTHY SKIN LPO, CAT, HMOX1 TSHR 4408/4885ALDH1A1 1238/4885SLC18A3 3569/4885
US-20060121133-A1 Antioxidant dietary supplement compositions and methods for maintaining healthy skin LPO, CAT, HMOX1 TSHR 4408/4885ALDH1A1 1238/4885SLC18A3 3569/4885
US-20030232893-A1 Method of treating rosacea HRH1, HRH2, CYP8B1 TSHR 1589/4885ALDH1A1 72/4885SLC18A3 4688/4885
US-20060045892-A1 Cosmetic compositions C1R, C5, C1S TSHR 2041/4885ALDH1A1 581/4885SLC18A3 4765/4885
US-20260098118-A1 Non-Softening Thermoplastic Polyurethanes PUF60, DCLRE1A, LRBA TSHR 3164/4885ALDH1A1 1304/4885SLC18A3 3779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.