Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17070218 | 1.00 | TSHR (0.56) | TSHRALDH1A1SLC18A3HSD11B1EPHX2 | |
| SCHEMBL787666 | 1.00 | TSHR (0.56) | TSHRALDH1A1SLC18A3HSD11B1EPHX2 | |
| SCHEMBL9396681 | 1.00 | TSHR (0.56) | TSHRALDH1A1SLC18A3HSD11B1EPHX2 | |
| SCHEMBL2450232 | 0.97 | TSHR (0.60) | TSHRALDH1A1SLC18A3EPHX2SHBG | |
| SCHEMBL12876612 | 0.97 | TSHR (0.60) | TSHRALDH1A1SLC18A3EPHX2SHBG | |
| Biphenyl SCHEMBL6720507 | 0.90 | TSHR (0.71) | TSHRALDH1A1SLC18A3HSD11B1CES2 | |
| SCHEMBL7077398 | 0.86 | TSHR (0.50) | TSHRALDH1A1EPHX2SHBG | |
| SCHEMBL219048 | 0.86 | TSHR (0.50) | TSHRALDH1A1EPHX2SHBG | |
| SCHEMBL7799823 | 0.86 | TSHR (0.50) | TSHRALDH1A1EPHX2SHBG | |
| SCHEMBL10879751 | 0.86 | TSHR (0.50) | TSHRALDH1A1EPHX2SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11781069-B2 | Liquid-crystal medium | MERCK PATENT GMBH (DE) | 2023-10-10 | — | — | US | disclosed |
| US-11718791-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2023-08-08 | — | — | US | disclosed |
| EP-3095833-B1 | NEMATIC LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY DEVICE USING SAME | DAINIPPON INK & CHEMICALS (JP) | 2018-06-27 | — | — | EP | disclosed |
| EP-2352061-A1 | ORIENTATION FILM, LIQUID CRYSTAL DISPLAY HAVING ORIENTATION FILM, AND METHOD FOR FORMING ORIENTATION FILM | Sharp Kabushiki Kaisha (JP) | 2011-08-03 | — | — | EP | disclosed |
| EP-1760068-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, OPTICALLY ANISOTROPIC MATERIAL AND OPTICAL DEVICE | Asahi Glass Company, Limited (JP) | 2007-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718791-B2 | Polymerisable compounds and the use thereof in liquid-crystal displays | VCL, ILK, LCP1 | TSHR 4856/4885ALDH1A1 4572/4885SLC18A3 1989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.