Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 1/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.49 |
| ▸ | CTSL | P07711 | 5/20 | 0.49 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.49 |
| ▸ | F2 | P00734 | 3/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.48 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2193250 | 0.94 | SSTR3 (0.57) | SSTR3SIRT2SIRT1CTSLSIRT3 | |
| SCHEMBL30541917 | 0.91 | SSTR3 (0.51) | SSTR3SIRT2SIRT1CTSLSIRT3 | |
| SCHEMBL17289476 | 0.91 | SIRT5 (0.55) | SSTR3SIRT2SIRT1SIRT3F2 | |
| SCHEMBL2268022 | 0.89 | SIRT5 (0.57) | SSTR3SIRT2SIRT1SIRT3F2 | |
| SCHEMBL27319796 | 0.89 | SSTR3 (0.52) | SSTR3 | |
| SCHEMBL7106396 | 0.89 | SSTR3 (0.52) | SSTR3 | |
| SCHEMBL521932 | 0.89 | SSTR3 (0.52) | SSTR3 | |
| Hydrochloric Acid SCHEMBL10884941 | 0.89 | SIRT5 (0.56) | SSTR3SIRT2SIRT1SIRT3F2 | |
| Hydrochloric Acid SCHEMBL10943848 | 0.89 | SIRT5 (0.56) | SSTR3SIRT2SIRT1SIRT3F2 | |
| Hydrochloric Acid SCHEMBL566787 | 0.88 | SSTR3 (0.51) | SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153413-B2 | High alkaline protease and use thereof | JAPAN AGENCY FOR MARINE-EARTH SCIENCE AND TECHNOLOGY (JP) | 2012-04-10 | — | — | US | disclosed |
| US-20110045570-A1 | NOVEL HIGH ALKALINE PROTEASE AND USE THEREOF | JAPAN AGENCY FOR MARINE-EARTH SCIENCE AND TECH. (JP) | 2011-02-24 | — | — | US | disclosed |