SCHEMBL521932

SCHEMBL521932

CC(C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)Nc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SSTR3 P32745 1/20 0.52
KISS1R Q969F8 1/20 0.46
BACE1 P56817 1/20 0.45
NPC1 O15118 1/20 0.44
TP53 P04637 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
FURIN P09958 3/20 0.43
NPY4R P50391 4/20 0.42
NPY1R P25929 3/20 0.42
NPY2R P49146 3/20 0.42
NPY5R Q15761 3/20 0.42
TMEM97 Q5BJF2 1/20 0.41
SIGMAR1 Q99720 1/20 0.41
F10 P00742 2/20 0.41
PSMB5 P28074 1/20 0.41
PDF Q9HBH1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7106396 1.00 SSTR3 (0.52) SSTR3KISS1RBACE1NPC1TP53
SCHEMBL27319796 1.00 SSTR3 (0.52) SSTR3KISS1RBACE1NPC1TP53
Hydrochloric Acid SCHEMBL566787 0.99 SSTR3 (0.51) SSTR3KISS1RBACE1NPC1TP53
SCHEMBL7888177 0.92 PDF (0.45) SSTR3NPC1TP53RAB9ASMN1; SMN2
SCHEMBL1269633 0.90 SSTR3 (0.51) SSTR3KISS1RSMN1; SMN2FURINNPY4R
4-Nitroaniline SCHEMBL27576311 0.90 BACE1 (0.47) SSTR3KISS1RBACE1NPC1TP53
SCHEMBL8128688 0.89 SSTR3 (0.49) SSTR3KISS1RFURINNPY4RNPY1R
SCHEMBL1088124 0.89 SSTR3 (0.54) SSTR3
SCHEMBL591280 0.87 NPC1 (0.51) SSTR3NPC1TP53RAB9ASMN1; SMN2
SCHEMBL701212 0.87 NPC1 (0.51) SSTR3NPC1TP53RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 275 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116718776-A Detect alpha 2 Macroglobulin kit 希肯生物技术(苏州)有限公司 2023-09-08 CN claimed
EP-2666854-B1 Recombinant elastase proteins and methods of manufacturing and use thereof PROTEON THERAPEUTICS INC (US) 2017-03-15 EP claimed
CN-120992537-A Method for determining titer of defibrase of agkistrodon acutus 吉林敖东药业集团延吉股份有限公司 2025-11-21 CN disclosed
CN-118225718-A Kit for detecting thrombin inhibitor 希肯生物技术(苏州)有限公司 2024-06-21 CN disclosed
CN-116718776-A Detect alpha 2 Macroglobulin kit 希肯生物技术(苏州)有限公司 2023-09-08 CN disclosed
US-9862956-B2 Expression and high-throughput screening of complex expressed DNA libraries in filamentous fungi DANISCO US INC. (US) 2018-01-09 US disclosed
US-20170037417-A9 EXPRESSION AND HIGH-THROUGHPUT SCREENING OF COMPLEX EXPRESSED DNA LIBRARIES IN FILAMENTOUS FUNGI DYADIC INTERNATIONAL, INC. (US) 2017-02-09 US disclosed
CN-104117059-B The application of Portunus trituberculatus Miers serine protease gene INSTITUTE OF OCEANOLOGY CHINESE ACADEMY OF SCIENCES (CN) 2016-05-04 CN disclosed
CN-102307582-B As protease inhibitor, for keeping bile acid and the biguanide of peptide integrity in intestinal AXCESS LTD. (JE) 2015-10-07 CN disclosed
CN-103525824-B Short octopus serpin OoSerpin gene and recombinant protein thereof and application SHANDONG PROVINCE MARINE LIVINGS RESEARCH INST. (CN) 2015-08-26 CN disclosed
US-20150211013-A1 EXPRESSION AND HIGH-THROUGHPUT SCREENING OF COMPLEX EXPRESSED DNA LIBRARIES IN FILAMENTOUS FUNGI DYADIC INTERNATIONAL, INC. (US) 2015-07-30 US disclosed
CN-86101066-A Process for producing novel trifluoromethyl ketone substituted peptide derivatives 1986-11-05 CN disclosed
EP-0048989-B1 PROCESS FOR DETERMINING INHIBITOR-ENZYME COMPLEXES CORNELL RESEARCH FOUNDATION, INC. (US) 1985-09-04 EP disclosed
US-4495278-A INACTIVATION OF VIRUS BY HEATING IN DRY STATE BAXTER TRAVENOL LABORATORIES, INC. (US) 1985-01-22 US disclosed
US-4480029-A LYOPHILIZED COMPLEX OF PROTEIN AND CALIBRATED TITER FOR INFECTIOUS VIRUS BAXTER TRAVENOL LABORATORIES, INC. (US) 1984-10-30 US disclosed
EP-0077355-A4 PROCESS FOR MAKING BLOOD CLOTTING ENZYME COMPOSITIONS. BAXTER TRAVENOL LAB (US) 1983-09-20 EP disclosed
EP-0077355-A1 PROCESS FOR MAKING BLOOD CLOTTING ENZYME COMPOSITIONS. BAXTER TRAVENOL LAB (US) 1983-04-27 EP disclosed
WO-1982003871-A1 PROCESS FOR MAKING NOVEL BLOOD CLOTTING ENZYME COMPOSITIONS BAXTER TRAVENOL LAB (US) 1982-11-11 WO disclosed
US-4252715-A SERINE PROTEASE, OLIGOPEPTIDE FOR DIAGNOSTIC DETERMINATION OF FACTOR XA AB KABI (SE) 1981-02-24 US disclosed
US-4162941-A CONTACTING WITH A PEPTIDE SUBSTRATE AND MEASURING THE ENZYMATIC HYDROLYSIS AB KABI (SE) 1979-07-31 US disclosed