Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | HSD17B3 | P37058 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.47 |
| ▸ | WNT3A | P56704 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10792888 | 0.94 | KMT2A (0.60) | KMT2AGSK3BHSD17B3NPC1RAB9A | |
| SCHEMBL9419411 | 0.90 | KMT2A (0.69) | KMT2AGSK3BHSD17B3NPC1RAB9A | |
| SCHEMBL8402203 | 0.88 | KMT2A (0.67) | KMT2AGSK3BHSD17B3NPC1RAB9A | |
| SCHEMBL2325573 | 0.86 | KMT2A (0.64) | KMT2AGSK3BNPC1RAB9AMEN1 | |
| SCHEMBL5849125 | 0.82 | KMT2A (0.78) | KMT2AGSK3BHSD17B3NPC1RAB9A | |
| SCHEMBL8525199 | 0.82 | HSD17B3 (0.72) | KMT2AGSK3BHSD17B3L3MBTL1TDP1 | |
| SCHEMBL17723259 | 0.82 | KMT2A (0.60) | KMT2AGSK3BHSD17B3NPC1RAB9A | |
| SCHEMBL2325662 | 0.82 | KMT2A (0.60) | KMT2AGSK3BHSD17B3NPC1RAB9A | |
| SCHEMBL10792399 | 0.82 | L3MBTL1 (0.55) | KMT2AHSD17B3NPC1RAB9AMEN1 | |
| SCHEMBL10790125 | 0.81 | HSD17B3 (0.51) | KMT2AHSD17B3NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0089769-B1 | 9-SUBSTITUTED CARBACYCLIN ANALOGUES | THE UPJOHN COMPANY (US) | 1986-10-01 | — | — | EP | disclosed |
| EP-0092352-B1 | 9-SUBSTITUTED CARBACYCLINS | THE UPJOHN COMPANY (US) | 1986-07-02 | — | — | EP | disclosed |
| EP-0086611-B1 | 9-SUBSTITUTED CARBACYCLIN ANALOGUES | THE UPJOHN COMPANY (US) | 1986-05-21 | — | — | EP | disclosed |
| EP-0087237-B1 | CARBACYCLIN ANALOGUES | THE UPJOHN COMPANY (US) | 1986-05-14 | — | — | EP | disclosed |
| US-4487961-A | ANTIULCER, ANTIASTHMA, ANTICOAGULANTS | THE UPJOHN COMPANY (US) | 1984-12-11 | — | — | US | disclosed |
| US-4352760-A | Organic compounds substituted heptadeca-5,9- and 5,10-dienoic acid | THE UPJOHN COMPANY (US) | 1982-10-05 | — | — | US | disclosed |
| US-4349690-A | ANTISECRETORY, ANTIULCER AGENTS, ANTICOAGULANTS AND ANTIAGGLOMERANTS | THE UPJOHN COMPANY (US) | 1982-09-14 | — | — | US | disclosed |
| US-4324889-A | 2,5-Inter-o-phenylene-3,4-dinor-6,9α-epoxy-6β-5-iodo-PGF1 amides | THE UPJOHN COMPANY (US) | 1982-04-13 | — | — | US | disclosed |
| US-4301078-A | SMOOTH MUSCLE STIMULATORS | THE UPJOHN COMPANY (US) | 1981-11-17 | — | — | US | disclosed |
| US-4289893-A | 2,5-Inter-O-phenylene-3,4-dinor-PGF2 compounds | THE UPJOHN COMPANY (US) | 1981-09-15 | — | — | US | disclosed |
| US-4160095-A | PROSTAGLANDINS; ANTIINFLAMMATORY AGENTS | THE UPJOHN COMPANY (US) | 1979-07-03 | — | — | US | disclosed |
| US-4157441-A | PROSTAGLANDINS, ANTIINFLAMMATORY AGENTS | THE UPJOHN COMPANY (US) | 1979-06-05 | — | — | US | disclosed |
| US-4151351-A | PROSTAGLANDINS, ANTIINFLAMMATORY | THE UPJOHN COMPANY (US) | 1979-04-24 | — | — | US | disclosed |
| US-4131738-A | 6-Hydroxy-PGE1 compounds | THE UPJOHN COMPANY (US) | 1978-12-26 | — | — | US | disclosed |
| US-4128713-A | 6,7-Didehydro-PGI1 compounds | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |
| US-4126744-A | PROSTACYCLIN, MUSCLE STIMULANTS, PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-11-21 | — | — | US | disclosed |
| US-4112224-A | PROSTAGLANDIN | THE UPJOHN COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-4109082-A | PROSTACYCLIN ANALOGS; SMOOTH MUSCLE STIMULATORS | THE UPJOHN COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4100192-A | Inter-phenylene-PG amides | THE UPJOHN COMPANY (US) | 1978-07-11 | — | — | US | disclosed |
| US-4097489-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-06-27 | — | — | US | disclosed |