SCHEMBL10882018

SCHEMBL10882018

CCCC(C)C(=O)OCC=Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.46
MMP2 P08253 1/20 0.46
MMP9 P14780 1/20 0.46
MMP12 P39900 1/20 0.46
CACNA1B Q00975 1/20 0.44
IDO1 P14902 2/20 0.44
PAM P19021 1/20 0.44
PPARA Q07869 3/20 0.43
PPARD Q03181 2/20 0.43
PPARG P37231 2/20 0.43
HTR2A P28223 3/20 0.41
NPC1 O15118 1/20 0.41
ALDH1A1 P00352 1/20 0.40
MAPT P10636 1/20 0.40
RECQL P46063 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5306720 0.83 MMP1 (0.51) MMP1MMP2MMP9MMP12CACNA1B
SCHEMBL827613 0.83 MMP1 (0.51) MMP1MMP2MMP9MMP12CACNA1B
SCHEMBL827614 0.83 MMP1 (0.51) MMP1MMP2MMP9MMP12CACNA1B
SCHEMBL22752013 0.81 MEN1 (0.41) PPARAPPARGNPC1ALDH1A1MAPT
SCHEMBL17633998 0.80 MMP1 (0.49) MMP1MMP2MMP9MMP12CACNA1B
SCHEMBL27608442 0.79 TSHR (0.56) MMP1MMP2MMP9MMP12CACNA1B
SCHEMBL356661 0.77 MMP1 (0.49) MMP1MMP2MMP9MMP12CACNA1B
SCHEMBL14763825 0.77 MMP1 (0.49) MMP1MMP2MMP9MMP12CACNA1B
SCHEMBL356660 0.77 MMP1 (0.49) MMP1MMP2MMP9MMP12CACNA1B
SCHEMBL1158019 0.76 MMP1 (0.51) MMP1MMP2MMP9MMP12CACNA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4613457-A COSMETICS, CLEANING COMPOUNDS BEGETABLE ODOR HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1986-09-23 US claimed
EP-0120274-B1 ESTERS OF 2-METHYLPENTANOIC ACID, THEIR PREPARATION AND USE AS FLAVOURING COMPOUNDS, AND FLAVOURING COMPOSITIONS CONTAINING THESE COMPOUNDS Henkel Kommanditgesellschaft auf Aktien (DE) 1986-09-17 EP claimed
EP-0120274-A1 Esters of 2-methylpentanoic acid, their preparation and use as flavouring compounds, and flavouring compositions containing these compounds Henkel Kommanditgesellschaft auf Aktien (DE) 1984-10-03 EP claimed
US-4613457-A COSMETICS, CLEANING COMPOUNDS BEGETABLE ODOR HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1986-09-23 US disclosed
EP-0120274-A1 Esters of 2-methylpentanoic acid, their preparation and use as flavouring compounds, and flavouring compositions containing these compounds Henkel Kommanditgesellschaft auf Aktien (DE) 1984-10-03 EP disclosed