SCHEMBL1088271

SCHEMBL1088271

C=Cc1ccc(OC(C)=O)c2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.47
SLC22A6 Q4U2R8 1/20 0.45
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 3/20 0.42
HPGD P15428 3/20 0.42
LMNA P02545 3/20 0.42
MAPT P10636 3/20 0.42
POLB P06746 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
TSHR P16473 3/20 0.42
PTGS2 P35354 3/20 0.42
PTGS1 P23219 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
ESR1 P03372 1/20 0.42
ITGB3 P05106 1/20 0.42
ITGA2B P08514 1/20 0.42
HMGB1 P09429 1/20 0.42
GGT1 P19440 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3628673 0.90 HTT (0.44) HTTSLC22A6MEN1KMT2AALDH1A1
SCHEMBL2649230 0.86 HTT (0.50) HTTSLC22A6MEN1KMT2AALDH1A1
SCHEMBL4444465 0.84 HTT (0.61) HTTSLC22A6MEN1KMT2AALDH1A1
SCHEMBL30002719 0.84 HTT (0.61) HTTSLC22A6MEN1KMT2AALDH1A1
SCHEMBL6564756 0.80 ELANE (0.39) MEN1KMT2AALDH1A1KDM4EHPGD
SCHEMBL58004 0.79 PTGS2 (0.52) SLC22A6MEN1KMT2AALDH1A1KDM4E
SCHEMBL30706195 0.79 PTGS2 (0.52) SLC22A6MEN1KMT2AALDH1A1KDM4E
Benzene SCHEMBL29242020 0.77 PTGS2 (0.55) MEN1KMT2AALDH1A1KDM4EHPGD
Ethylene SCHEMBL27547726 0.77 PTGS2 (0.50) SLC22A6MEN1KMT2AALDH1A1KDM4E
Methane SCHEMBL27458309 0.77 PTGS2 (0.50) SLC22A6MEN1KMT2AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109843853-B Composition and method for manufacturing device using the same 东洋合成工业株式会社 2022-09-20 CN disclosed
US-11142495-B2 Composition and method for manufacturing device using same TOYO GOSEI CO., LTD. (JP) 2021-10-12 US disclosed
US-20200048191-A1 COMPOSITION AND METHOD FOR MANUFACTURING DEVICE USING SAME TOYO GOSEI CO., LTD. (JP) 2020-02-13 US disclosed
US-8535872-B2 Thermally cured underlayer for lithographic application FUJIFILM ELECTRONIC MATERIALS, U.S.A., INC. (US) 2013-09-17 US disclosed
US-20120178871-A1 THERMALLY CURED UNDERLAYER FOR LITHOGRAPHIC APPLICATION DE BINOD B (US) 2012-07-12 US disclosed
US-8153346-B2 Hydroxyl containing polymer, amino crosslinking agent and thermal acid generator; undercoating for multilayer lithography material FUJIFILM ELECTRONIC MATERIALS, U.S.A., INC. (US) 2012-04-10 US disclosed
WO-2008103776-A2 THERMALLY CURED UNDERLAYER FOR LITHOGRAPHIC APPLICATION FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2008-08-28 WO disclosed
US-20080206676-A1 THERMALLY CURED UNDERLAYER FOR LITHOGRAPHIC APPLICATION FUJIFILM ELECTRONIC MATERIALS, U.S.A, INC 2008-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200048191-A1 COMPOSITION AND METHOD FOR MANUFACTURING DEVICE USING SAME LBR, LMTK2, MMS19 HTT 1704/4885SLC22A6 4143/4885MEN1 3312/4885
US-11142495-B2 Composition and method for manufacturing device using same LBR, LMTK2, MMS19 HTT 1704/4885SLC22A6 4143/4885MEN1 3312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.