SCHEMBL10883243

SCHEMBL10883243

O=C1C2CCCCC2C(=O)N1CN1C(=O)C2CCCCC2C1=O

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
HTT P42858 1/20 0.46
TP53 P04637 1/20 0.40
RAB9A P51151 2/20 0.38
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
MT-CO2 P00403 1/20 0.37
ALOX5 P09917 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17532412 0.84 ALDH1A1 (0.53) ALDH1A1HTTTP53RAB9AKMT2A
SCHEMBL17532416 0.80 ALDH1A1 (0.50) ALDH1A1HTTRAB9ALMNATDP1
SCHEMBL1101920 0.80 ALDH1A1 (0.50) ALDH1A1HTTTP53RAB9AKDM4E
SCHEMBL10869246 0.80 ALDH1A1 (0.50) ALDH1A1HTTTP53RAB9AKDM4E
SCHEMBL17532462 0.78 ALDH1A1 (0.48) ALDH1A1HTTTP53RAB9AKDM4E
SCHEMBL1147308 0.78 ALDH1A1 (0.48) ALDH1A1HTTTP53RAB9AKMT2A
SCHEMBL17532423 0.78 ALDH1A1 (0.49) ALDH1A1HTTTP53RAB9ALMNA
SCHEMBL10948563 0.78 ALDH1A1 (0.49) ALDH1A1HTTTP53RAB9ALMNA
SCHEMBL7286002 0.77 ALDH1A1 (0.47) ALDH1A1HTTTP53RAB9AKDM4E
SCHEMBL1147309 0.77 ALDH1A1 (0.47) ALDH1A1HTTTP53RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160039994-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-02-11 US disclosed
US-8772383-B2 Material for alignment layer of liquid crystal display SHENZHEN CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2014-07-08 US disclosed
US-20140024751-A1 MATERIAL FOR ALIGNMENT LAYER OF LIQUID CRYSTAL DISPLAY SHENZHEN CHINA STAR OPTOELECTRICS TECHNOLOGY CO., LTD. (CN) 2014-01-23 US disclosed
EP-0091669-B1 PROCESS FOR PRODUCING POROUS, FILM-LIKE OR FIBROUS STRUCTURE OF AROMATIC POLYESTER TEIJIN LIMITED (JP) 1986-10-01 EP disclosed
EP-0057387-B1 PRODUCTION OF A FILM-LIKE OR FIBROUS STRUCTURE OF AN AROMATIC POLYESTER TEIJIN LIMITED (JP) 1986-05-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160039994-A1 OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE VCL, L1CAM, F12 ALDH1A1 2275/4885HTT 3829/4885TP53 4307/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.