Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.37 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208604 | 0.72 | CYP2C9 (0.41) | SMN1; SMN2TSHRCES1NR1H2MEN1 | |
| SCHEMBL2343845 | 0.72 | RAD51 (0.51) | P2RX7PTGS2FGFR1FGFR2FGFR4 | |
| SCHEMBL11340112 | 0.69 | SMN1; SMN2 (0.40) | SMN1; SMN2TSHRP2RX7PTGS2FGFR1 | |
| SCHEMBL11569131 | 0.68 | PDE4B (0.55) | SMN1; SMN2P2RX7PTGS2FGFR1FGFR2 | |
| SCHEMBL4837133 | 0.67 | PTGS2 (0.56) | SMN1; SMN2TSHRPTGS2 | |
| SCHEMBL31415662 | 0.64 | PTGS2 (0.44) | SMN1; SMN2TSHRP2RX7PTGS2FGFR1 | |
| Biphenyl SCHEMBL3791855 | 0.64 | TSHR (0.84) | SMN1; SMN2TSHRLMNAGAATDP1 | |
| SCHEMBL22666659 | 0.63 | TSHR (0.58) | SMN1; SMN2TSHRPTGS2LMNACA1 | |
| SCHEMBL20534355 | 0.63 | TSHR (0.58) | SMN1; SMN2TSHRPTGS2LMNACA1 | |
| SCHEMBL25613492 | 0.63 | TSHR (0.58) | SMN1; SMN2TSHRPTGS2LMNACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0093085-B1 | PROCESS FOR THE PREPARATION OF A STORAGE-STABLE, MISCIBLE HARDENER FOR ACRYLIC ADHESIVE RESINS | CIBA-GEIGY AG (CH) | 1986-07-02 | — | — | EP | disclosed |
| US-4496694-A | BLEND OF POLYMERIZABLE MONOMER AND ALDEHYDE/AMINE CONDENSATION PRODUCT | CIBA-GEIGY CORPORATION (US) | 1985-01-29 | — | — | US | disclosed |
| EP-0093085-A2 | Process for the preparation of a storage-stable, miscible hardener for acrylic adhesive resins | CIBA-GEIGY AG (CH) | 1983-11-02 | — | — | EP | disclosed |