Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CTSG | P08311 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27559173 | 0.75 | ALPL (0.44) | CYP2C9MAPK1CYP1A2HIF1ANR1H2 | |
| SCHEMBL10884514 | 0.72 | SMN1; SMN2 (0.41) | NR1H2KMT2AALDH1A1CES1MEN1 | |
| SCHEMBL29107423 | 0.72 | CYP1A2 (0.44) | CYP2C9MAPK1CYP1A2HIF1AIDH1 | |
| SCHEMBL11573340 | 0.65 | CYP2C9 (0.42) | CYP2C9MAPK1CYP1A2HIF1ANR1H2 | |
| Diphenylmethane SCHEMBL9099676 | 0.64 | TSHR (0.73) | IDH1PLA2G10PLA2G2AALDH1A1TSHR | |
| SCHEMBL3044017 | 0.64 | HIF1A (0.48) | CYP2C9MAPK1CYP1A2HIF1ANR1H2 | |
| Diphenylmethane SCHEMBL9244248 | 0.63 | CALM1 (0.60) | IDH1KMT2APLA2G10PLA2G2AALDH1A1 | |
| SCHEMBL3151100 | 0.63 | TSHR (0.62) | IDH1PLA2G10PLA2G2AALDH1A1CES1 | |
| Diphenylmethane SCHEMBL27942273 | 0.62 | CALM1 (0.67) | IDH1F2PLGELANECTSG | |
| SCHEMBL29740732 | 0.60 | BCL2 (0.50) | CYP2C9MAPK1CYP1A2HIF1ANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4287106-A | ACRYLATE MONOMER, DIENE POLYMER | CIBA-GEIGY CORPORATION (US) | 1981-09-01 | — | — | US | claimed |
| EP-0008110-B1 | ADHESIVES OR ADHESIVE CONSTITUENTS AND THEIR USE FOR BONDING TWO SURFACES | CIBA-GEIGY AG (CH) | 1983-04-06 | — | — | EP | disclosed |
| US-4287106-A | ACRYLATE MONOMER, DIENE POLYMER | CIBA-GEIGY CORPORATION (US) | 1981-09-01 | — | — | US | disclosed |