SCHEMBL10884652

SCHEMBL10884652

CC(C)c1cc(C(C)(C)CC(C)(C)P(=O)(O)O)cc(C(C)C)c1O

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.42
GABRB1 P18505 4/20 0.42
GABRB2 P47870 1/20 0.42
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
GAA P10253 4/20 0.40
GSR P00390 1/20 0.37
PTPN5 P54829 1/20 0.36
HTT P42858 2/20 0.34
LMNA P02545 1/20 0.34
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2B6 P20813 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11049251 0.80 ESR1 (0.41) CA1CA2PTPN5ALDH1A1CYP1A2
SCHEMBL200830 0.80 CA1 (0.54) GABRA1GABRB1GABRB2CA1CA2
SCHEMBL10410104 0.78 GABRA1 (0.42) GABRA1GABRB1GABRB2CA1CA2
SCHEMBL27728975 0.72 CYP3A4 (0.48) GABRA1GABRB1GABRB2CA1CA2
SCHEMBL10410219 0.72 GABRA1 (0.39) GABRA1GABRB1GABRB2CA1CA2
SCHEMBL10410131 0.71 SHBG (0.60) LMNAALDH1A1CYP3A4
Phosphonic Acid SCHEMBL10410103 0.71 GABRA1 (0.44) GABRA1GABRB1GABRB2CA1CA2
Phosphonic Acid SCHEMBL10410221 0.70 GABRA1 (0.43) GABRA1GABRB1GABRB2CA1CA2
SCHEMBL199772 0.69 CA1 (0.58) GABRA1GABRB1GABRB2CA1CA2
SCHEMBL299993 0.69 CA1 (0.58) GABRA1GABRB1GABRB2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0106799-B1 PHENOLS AND THEIR PREPARATION CIBA-GEIGY AG (CH) 1986-03-19 EP disclosed
EP-0106799-A1 Phenols and their preparation CIBA-GEIGY AG (CH) 1984-04-25 EP disclosed