Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 7/20 | 0.67 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.67 |
| ▸ | GNMT | Q14749 | 1/20 | 0.61 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | HRH1 | P35367 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11215188 | 0.88 | ADORA2A (0.57) | ADORA2AADORA2BADORA3 | |
| SCHEMBL10888025 | 0.88 | ADORA2A (0.57) | ADORA2AADORA2BADORA3 | |
| SCHEMBL14470609 | 0.87 | ADORA3 (0.63) | GNMTADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL18402898 | 0.87 | ADORA3 (0.63) | GNMTADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL10886624 | 0.86 | AHCY (0.65) | AHCYTMEM97HIF1ASIGMAR1HSP90B1 | |
| SCHEMBL10886586 | 0.85 | AHCY (0.63) | AHCYTMEM97HIF1ASIGMAR1HSP90B1 | |
| SCHEMBL10886571 | 0.85 | AHCY (0.63) | AHCYTMEM97HIF1ASIGMAR1HSP90B1 | |
| SCHEMBL10888062 | 0.85 | AHCY (0.63) | AHCYTMEM97HIF1ASIGMAR1HSP90B1 | |
| SCHEMBL10884413 | 0.85 | AHCY (0.67) | AHCYTMEM97HIF1ASIGMAR1HSP90B1 | |
| SCHEMBL10886149 | 0.84 | AHCY (0.63) | AHCYTMEM97HIF1ASIGMAR1GNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071926-B1 | NEW RIBOFURANURONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-08 | — | — | EP | disclosed |
| US-4479942-A | Tetrahydrofurnancarboxylic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-30 | — | — | US | disclosed |
| EP-0071926-A1 | New ribofuranuronic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-02-16 | — | — | EP | disclosed |