Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 6/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | NPEPPS | P55786 | 2/20 | 0.49 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11196402 | 0.88 | NPEPPS (0.47) | NPEPPSADORA2B | |
| SCHEMBL10883806 | 0.88 | NPEPPS (0.47) | NPEPPSADORA2B | |
| SCHEMBL11060550 | 0.84 | AHCY (0.60) | AHCYHIF1ATMEM97SIGMAR1ADORA3 | |
| SCHEMBL10885013 | 0.81 | AHCY (0.51) | AHCYHIF1ATMEM97SIGMAR1ADORA3 | |
| SCHEMBL10885676 | 0.80 | AHCY (0.55) | AHCYHIF1ATMEM97SIGMAR1NPEPPS | |
| SCHEMBL11060590 | 0.79 | NPEPPS (0.51) | AHCYHIF1ATMEM97SIGMAR1NPEPPS | |
| SCHEMBL10886624 | 0.79 | AHCY (0.65) | AHCYHIF1ATMEM97SIGMAR1ADORA3 | |
| SCHEMBL10888062 | 0.78 | AHCY (0.63) | AHCYHIF1ATMEM97SIGMAR1ADORA3 | |
| SCHEMBL10884594 | 0.78 | NPEPPS (0.50) | AHCYHIF1ATMEM97SIGMAR1NPEPPS | |
| SCHEMBL10884413 | 0.78 | AHCY (0.67) | AHCYHIF1ATMEM97SIGMAR1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071926-B1 | NEW RIBOFURANURONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-08 | — | — | EP | disclosed |
| US-4479942-A | Tetrahydrofurnancarboxylic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-30 | — | — | US | disclosed |