SCHEMBL10885167

SCHEMBL10885167

O=C(Nc1ccc(Cl)cc1)c1ccc2ccccc2c1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLG P00747 2/20 0.71
KLK1 P06870 2/20 0.71
KLK6 Q92876 2/20 0.71
ALOX15 P16050 1/20 0.63
TNF P01375 2/20 0.62
NOD1 Q9Y239 2/20 0.62
NPC1 O15118 4/20 0.61
RAB9A P51151 4/20 0.61
P2RX1 P51575 1/20 0.60
P2RX3 P56373 1/20 0.60
P2RX4 Q99571 1/20 0.60
P2RX7 Q99572 1/20 0.60
MEN1 O00255 6/20 0.59
KMT2A Q03164 6/20 0.59
MAPT P10636 4/20 0.59
KDM4E B2RXH2 3/20 0.59
LMNA P02545 2/20 0.59
HTT P42858 1/20 0.59
POLB P06746 2/20 0.56
DEGS1 O15121 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8438773 0.88 PLG (0.74) PLGKLK1KLK6ALOX15TNF
SCHEMBL5383147 0.85 PLG (0.75) PLGKLK1KLK6ALOX15TNF
SCHEMBL14428123 0.83 PLG (0.60) PLGKLK1KLK6ALOX15TNF
SCHEMBL5383141 0.83 PLG (0.71) PLGKLK1KLK6ALOX15TNF
SCHEMBL21273938 0.83 PLG (1.00) PLGKLK1KLK6ALOX15TNF
SCHEMBL10336856 0.83 PLG (0.67) PLGKLK1KLK6ALOX15TNF
SCHEMBL14440320 0.83 PLG (0.67) PLGKLK1KLK6ALOX15TNF
Hydrochloric Acid SCHEMBL22798886 0.83 PLG (1.00) PLGKLK1KLK6ALOX15TNF
SCHEMBL11329513 0.82 MEN1 (0.74) PLGKLK1KLK6ALOX15TNF
SCHEMBL14428018 0.82 PLG (0.66) PLGKLK1KLK6ALOX15TNF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0084890-B1 DIAZOTYPE HEAT DEVELOPMENT RECORDING MEDIUM Toppan Printing Co., Ltd. (JP) 1986-05-21 EP disclosed
US-4487826-A EXCELLENT SHELF LIFE AND HEAT SENSITIVITY TOPPAN PRINTING CO., LTD. (JP) 1984-12-11 US disclosed
EP-0084890-A1 Diazotype heat development recording medium Toppan Printing Co., Ltd. (JP) 1983-08-03 EP disclosed