SCHEMBL8438773

SCHEMBL8438773

O=C(Nc1ccccc1)c1ccc2ccccc2c1O

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLG P00747 2/20 0.74
KLK1 P06870 2/20 0.74
KLK6 Q92876 2/20 0.74
NPC1 O15118 3/20 0.72
RAB9A P51151 3/20 0.72
P2RX1 P51575 1/20 0.66
P2RX3 P56373 1/20 0.66
P2RX4 Q99571 1/20 0.66
P2RX7 Q99572 1/20 0.66
MEN1 O00255 6/20 0.65
KMT2A Q03164 6/20 0.65
MAPT P10636 3/20 0.65
POLB P06746 2/20 0.65
LMNA P02545 2/20 0.65
TNF P01375 2/20 0.65
NOD1 Q9Y239 2/20 0.65
ALOX15 P16050 1/20 0.65
LDHA P00338 1/20 0.64
EGLN1 Q9GZT9 1/20 0.62
GAA P10253 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11329513 0.90 MEN1 (0.74) PLGKLK1KLK6NPC1RAB9A
SCHEMBL5383147 0.88 PLG (0.75) PLGKLK1KLK6NPC1RAB9A
SCHEMBL10885167 0.88 PLG (0.71) PLGKLK1KLK6NPC1RAB9A
SCHEMBL10336856 0.85 PLG (0.67) PLGKLK1KLK6NPC1RAB9A
Hydrochloric Acid SCHEMBL22798886 0.85 PLG (1.00) PLGKLK1KLK6NPC1RAB9A
SCHEMBL14440320 0.85 PLG (0.67) PLGKLK1KLK6NPC1RAB9A
SCHEMBL5383141 0.85 PLG (0.71) PLGKLK1KLK6NPC1RAB9A
SCHEMBL21273938 0.85 PLG (1.00) PLGKLK1KLK6NPC1RAB9A
SCHEMBL14428018 0.84 PLG (0.66) PLGKLK1KLK6NPC1RAB9A
SCHEMBL10888080 0.84 PLG (0.66) PLGKLK1KLK6NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0570974-B1 Color photographic materials and methods containing DIR or DIAR couplers and carbonamide coupler solvents EASTMAN KODAK CO (US) 1998-11-18 EP claimed
EP-0570973-B1 Color photographic materials and methods containing DIR or DIAR couplers and phenolic coupler solvents EASTMAN KODAK CO (US) 1998-11-18 EP claimed
EP-0655648-B1 Photographic elements comprising 2-phenylcarbomoyl-1-naphthol image-modifying couplers yielding dyes resistant to crystallization and reduction EASTMAN KODAK CO (US) 1998-06-10 EP claimed
EP-0651288-B1 Photographic elements comprising 2-phenylcarbamoyl-1-naphthol image-modifying couplers yielding dyes resistant to crystallization and reduction EASTMAN KODAK CO (US) 1997-02-19 EP claimed
EP-0636934-B1 Photographic elements comprising 2-phenylcarbamoyl-1-naphthol image-modifying couplers yielding dyes resistant to crystallization and reduction EASTMAN KODAK CO (US) 1997-02-19 EP claimed
US-5521057-A COLOR FILMS EASTMAN KODAK COMPANY (US) 1996-05-28 US claimed
US-5514530-A IMPROVED COLOR DENSITY, COLOR NEGATIVE FILMS EASTMAN KODAK COMPANY (US) 1996-05-07 US claimed
US-5510235-A LOW TEMPERATURE STORAGE STABILITY, RESISTANCE TO REDUCTION IN SEASONED BLEACHES EASTMAN KODAK COMPANY (US) 1996-04-23 US claimed
US-5506094-A Photographic elements comprising 2-phenylcarbamoyl-1-naphthol image-modifying couplers yielding dyes resistant to crystallization and reduction EASTMAN KODAK COMPANY (US) 1996-04-09 US claimed
US-5451496-A Color photographic materials and methods containing DIR or DIAR couplers and phenolic coupler solvents EASTMAN KODAK COMPANY (US) 1995-09-19 US claimed
EP-0636934-A1 Photographic elements comprising 2-phenylcarbamoyl-1-naphthol image-modifying couplers yielding dyes resistant to crystallization and reduction EASTMAN KODAK COMPANY (US) 1995-02-01 EP claimed
EP-0636936-A1 Photographic elements comprising 2-phenylcarbamoyl-1-naphthol image-modifying couplers yielding dyes resistant to crystallization and reduction EASTMAN KODAK COMPANY (US) 1995-02-01 EP claimed
US-5378593-A DIR=development inhibitor releasing couplers; DIAR=timed development inhibiting releasing couplers EASTMAN KODAK COMPANY (US) 1995-01-03 US claimed
EP-0570973-A1 Color photographic materials and methods containing DIR or DIAR couplers and phenolic coupler solvents EASTMAN KODAK COMPANY (US) 1993-11-24 EP claimed
EP-0570974-A1 Color photographic materials and methods containing DIR or DIAR couplers and carbonamide coupler solvents EASTMAN KODAK COMPANY (US) 1993-11-24 EP claimed
US-5244860-A PRESSURE-SENSITIVE RECORDING AND TRANSFER MATERIAL CIBA-GEIGY CORPORATION (US) 1993-09-14 US claimed
EP-0377406-B1 PRESSURE-SENSITIVE OR HEAT-SENSITIVE RECORDING MATERIAL CIBA-GEIGY AG (CH) 1993-06-09 EP claimed
EP-0373110-B1 PRESSURE-SENSITIVE OR HEAT-SENSITIVE RECORDING MATERIAL CIBA-GEIGY AG (CH) 1993-04-21 EP claimed
US-5024988-A Color reaction system comprising a polycyclic heterocyclic compound, a leuko dye to form a chromogen with the first compound, a Lewis acid and developer CIBA-GEIGY CORPORATION (US) 1991-06-18 US claimed
US-5013707-A Pressure- or heat-sensitive recording material CIBA-GEIGY CORPORATION (US) 1991-05-07 US claimed