Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 2/20 | 0.67 |
| ▸ | KLK1 | P06870 | 2/20 | 0.67 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 8/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.57 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.57 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.57 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.57 |
| ▸ | TNF | P01375 | 2/20 | 0.54 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438773 | 0.85 | PLG (0.74) | PLGKLK1KLK6MEN1KMT2A | |
| SCHEMBL14428018 | 0.85 | PLG (0.66) | PLGKLK1KLK6MEN1KMT2A | |
| SCHEMBL10336856 | 0.83 | PLG (0.67) | PLGKLK1KLK6MEN1KMT2A | |
| SCHEMBL10885167 | 0.83 | PLG (0.71) | PLGKLK1KLK6MEN1KMT2A | |
| SCHEMBL5383147 | 0.83 | PLG (0.75) | PLGKLK1KLK6MEN1KMT2A | |
| SCHEMBL14112088 | 0.83 | MEN1 (0.80) | PLGKLK1KLK6MEN1KMT2A | |
| SCHEMBL10888080 | 0.82 | PLG (0.66) | PLGKLK1KLK6MEN1KMT2A | |
| SCHEMBL12305600 | 0.81 | PLG (0.64) | PLGKLK1KLK6MEN1KMT2A | |
| SCHEMBL21273938 | 0.81 | PLG (1.00) | PLGKLK1KLK6MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL22798886 | 0.81 | PLG (1.00) | PLGKLK1KLK6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197533-A1 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-08-23 | — | — | US | disclosed |
| US-7223759-B2 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | ANADYS PHARMACEUTICALS, INC. (US) | 2007-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197533-A1 | Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds | DDC, DPP3, AMPD3 | PLG 4709/4885KLK1 2917/4885KLK6 2107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.