⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11314342 | 0.80 | TDP1 (0.55) | — | |
| SCHEMBL5094357 | 0.74 | — | — | |
| SCHEMBL28419463 | 0.74 | — | — | |
| SCHEMBL1623475 | 0.71 | LMNA (0.44) | — | |
| SCHEMBL2230381 | 0.71 | — | — | |
| SCHEMBL27458020 | 0.71 | — | — | |
| SCHEMBL733686 | 0.69 | — | — | |
| E968 SCHEMBL28817470 | 0.67 | LMNA (0.44) | — | |
| SCHEMBL13276320 | 0.65 | — | — | |
| SCHEMBL12275929 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057988-B1 | BANDAGES | Smith and Nephew Associated Companies p.l.c. (GB) | 1986-11-26 | — | — | EP | disclosed |
| US-4427003-A | COATING FLEXIBLE FABRIC WITH WATER ABSORBING POLYURETHANE AND CATALYST, AND HARDENING | SMITH & NEPHEW ASSOCIATED COMPANIES LTD. (GB) | 1984-01-24 | — | — | US | disclosed |
| EP-0057988-A2 | Bandages | Smith and Nephew Associated Companies p.l.c. (GB) | 1982-08-18 | — | — | EP | disclosed |