⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29429791 | 0.82 | LMNA (0.53) | — | |
| SCHEMBL29409228 | 0.80 | LMNA (0.50) | — | |
| SCHEMBL38654734 | 0.80 | LMNA (0.58) | — | |
| SCHEMBL13841279 | 0.73 | — | — | |
| SCHEMBL10885177 | 0.71 | — | — | |
| SCHEMBL5013801 | 0.71 | — | — | |
| SCHEMBL23266184 | 0.69 | LMNA (0.50) | — | |
| SCHEMBL10022040 | 0.69 | LMNA (0.50) | — | |
| SCHEMBL31374574 | 0.69 | LMNA (0.36) | — | |
| Mannitol SCHEMBL28979520 | 0.69 | LMNA (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9345804-B2 | S-nitrosothiol-generating skin dressings | INSENSE LIMITED (GB) | 2016-05-24 | — | — | US | disclosed |
| US-20150086651-A1 | S-NITROSOTHIOL-GENERATING SKIN DRESSINGS | SUSSEX RESEARCH LIMITED (GB) | 2015-03-26 | — | — | US | disclosed |
| EP-2173391-B1 | IMPROVEMENTS RELATING TO SKIN DRESSINGS | INSENSE LTD (GB) | 2011-08-03 | — | — | EP | disclosed |
| US-20100197802-A1 | SKIN DRESSINGS | INSENSE LIMITED (GB) | 2010-08-05 | — | — | US | disclosed |
| EP-2173391-A2 | IMPROVEMENTS RELATING TO SKIN DRESSINGS | Insense Limited (GB) | 2010-04-14 | — | — | EP | disclosed |
| WO-2009019499-A2 | IMPROVEMENTS RELATING TO SKIN DRESSINGS | INSENSE LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |