Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.34 |
| ▸ | PTP4A1 | Q93096 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10999487 | 0.86 | CYP3A4 (0.39) | CYP3A4PTP4A3PTP4A1SMN1; SMN2PTP4A2 | |
| SCHEMBL10888016 | 0.83 | CYP3A4 (0.34) | CYP3A4PTP4A3PTP4A1SMN1; SMN2PTP4A2 | |
| SCHEMBL9451830 | 0.79 | ALDH1A1 (0.39) | CYP3A4PTP4A3PTP4A1SMN1; SMN2PTP4A2 | |
| SCHEMBL10928922 | 0.77 | ESR1 (0.46) | CYP3A4 | |
| SCHEMBL10935249 | 0.73 | CYP3A4 (0.41) | CYP3A4PTP4A3PTP4A1MEN1KMT2A | |
| SCHEMBL6153276 | 0.73 | CYP3A4 (0.42) | CYP3A4SMN1; SMN2MEN1KMT2AAPP | |
| SCHEMBL2127295 | 0.71 | CYP3A4 (0.46) | CYP3A4SMN1; SMN2MEN1KMT2AAPP | |
| SCHEMBL20398539 | 0.69 | CYP3A4 (0.53) | CYP3A4SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL9174748 | 0.69 | CYP3A4 (0.49) | CYP3A4PTP4A3PTP4A1SMN1; SMN2MEN1 | |
| SCHEMBL10884994 | 0.69 | ALDH1A1 (0.36) | CYP3A4SMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4611892-A | Synthetic resin ophthalmic lens having a surface hard coat | SEIKO EPSON CORPORATION (JP) | 1986-09-16 | — | — | US | claimed |
| US-4611892-A | Synthetic resin ophthalmic lens having a surface hard coat | SEIKO EPSON CORPORATION (JP) | 1986-09-16 | — | — | US | disclosed |