SCHEMBL2127295

SCHEMBL2127295

C=CCOC(=O)Oc1cc(OC(=O)OCC=C)cc(OC(=O)OCC=C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.46
TSHR P16473 4/20 0.40
ALDH1A1 P00352 4/20 0.40
HSD17B10 Q99714 3/20 0.40
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
APP P05067 1/20 0.39
NPSR1 Q6W5P4 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
PKM P14618 1/20 0.36
SNCA P37840 1/20 0.36
KDM4E B2RXH2 3/20 0.36
HPGD P15428 2/20 0.36
TP53 P04637 1/20 0.36
MAPT P10636 5/20 0.35
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
POLB P06746 2/20 0.35
MAPK1 P28482 2/20 0.35
RHOA P61586 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6152555 0.89 CYP3A4 (0.49) CYP3A4TSHRALDH1A1HSD17B10MEN1
SCHEMBL10870487 0.88 CYP3A4 (0.50) CYP3A4TSHRALDH1A1HSD17B10MEN1
SCHEMBL7946937 0.85 CYP3A4 (0.44) CYP3A4TSHRALDH1A1HSD17B10MEN1
SCHEMBL10820448 0.84 TTR (0.56) CYP3A4MEN1KMT2AAPPSMN1; SMN2
SCHEMBL545547 0.82 CYP3A4 (0.55) CYP3A4TSHRALDH1A1HSD17B10MEN1
SCHEMBL6152948 0.82 CYP3A4 (0.46) CYP3A4TSHRALDH1A1HSD17B10MEN1
SCHEMBL10874091 0.82 CASP1 (0.43) CYP3A4TSHRALDH1A1HSD17B10MEN1
SCHEMBL16007676 0.82 LMNA (0.46) CYP3A4TP53LMNA
Bicarbonate SCHEMBL23748029 0.81 CYP3A4 (0.53) CYP3A4TSHRALDH1A1HSD17B10MEN1
Formaldehyde SCHEMBL28598678 0.81 CYP3A4 (0.53) CYP3A4TSHRALDH1A1HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304889-A1 CLEAVABLE MULTI-ALCOHOL-BASED MICROCAPSULES FIRMENICH SA (CH) 2025-10-02 US disclosed
US-12365853-B2 Cleavable multi-alcohol-based microcapsules FIRMENICH SA (CH) 2025-07-22 US disclosed
EP-3921075-B1 CLEAVABLE MULTI-ALCOHOL-BASED MICROCAPSULES FIRMENICH & CIE (CH) 2024-06-12 EP disclosed
US-20230250369-A9 CLEAVEABLE MULTI-ALCOHOL-BASED MICROCAPSULES FIRMENICH SA (CH) 2023-08-10 US disclosed
US-20220169954-A1 CLEAVEABLE MULTI-ALCOHOL-BASED MICROCAPSULES FIRMENICH & CIE (CH) 2022-06-02 US disclosed
EP-3548541-B1 DUAL CURE MONOMERS 3M INNOVATIVE PROPERTIES CO (US) 2022-05-18 EP disclosed
US-11021574-B2 Dual cure monomers 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-06-01 US disclosed
EP-2958538-B1 STABILIZED DENTAL IMPRESSION COMPOSITION, KIT OF PARTS AND USE THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2020-04-29 EP disclosed
US-20200062908-A1 Dual Cure Monomers 3M INNOVATIVE PROPERTIES COMPANY 2020-02-27 US disclosed
US-9549881-B2 Stabilized dental impression composition, kit of parts and use thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-01-24 US disclosed
US-20110160332-A1 CURABLE SILICONE IMPRESSION MATERIALS WITH HIGH TEAR STRENGTH AND LOW CONSISTENCY 3M ESPE 2011-06-30 US disclosed
US-7968645-B2 Curable silicone impression materials with high tear strength and low consistency 3M ESPE AG (DE) 2011-06-28 US disclosed
US-20100184881-A1 HYDROPHILIZED CURABLE SILICONE IMPRESSION MATERIALS WITH IMPROVED STORAGE BEHAVIOR 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-07-22 US disclosed
US-20090047620-A1 ANTI-MICROBIAL DENTAL IMPRESSION MATERIAL 3M INNOVATIVE PROPERTIER COMPANY 2009-02-19 US disclosed
EP-1948119-A1 ANTI-MICROBIAL DENTAL IMPRESSION MATERIAL 3M Innovative Properties Company (US) 2008-07-30 EP disclosed
WO-2007061647-A1 ANTI-MICROBIAL DENTAL IMPRESSION MATERIAL 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-05-31 WO disclosed
EP-1787627-A1 Anti-microbial dental impression material 3M Innovative Properties Company (US) 2007-05-23 EP disclosed
US-20070060717-A1 Curable silicone impression materials with high tear strength and low consistency 3M DEUTSCHLAND GMBH (DE) 2007-03-15 US disclosed
EP-1475069-A1 Curable silicone impression materials with high tear strength and low consistency 3M Espe AG (DE) 2004-11-10 EP disclosed
US-6335413-B1 DENTISTRY ESPE DENTAL AG (DE) 2002-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100184881-A1 HYDROPHILIZED CURABLE SILICONE IMPRESSION MATERIALS WITH IMPROVED STORAGE BEHAVIOR PIEZO1, IP6K1, IP6K2 CYP3A4 4766/4885TSHR 3484/4885ALDH1A1 3151/4885
US-20110160332-A1 CURABLE SILICONE IMPRESSION MATERIALS WITH HIGH TEAR STRENGTH AND LOW CONSISTENCY SMCHD1, RAD51, SRI CYP3A4 4333/4885TSHR 2033/4885ALDH1A1 3868/4885
US-20090047620-A1 ANTI-MICROBIAL DENTAL IMPRESSION MATERIAL CNDP2, POLL, AAAS CYP3A4 3195/4885TSHR 4321/4885ALDH1A1 4454/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.