Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 9/20 | 0.65 |
| ▸ | DOT1L | Q8TEK3 | 5/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10887158 | 1.00 | AHCY (0.65) | AHCYDOT1LHIF1ATMEM97SIGMAR1 | |
| SCHEMBL11052640 | 0.96 | AHCY (0.60) | AHCYDOT1LHIF1ATMEM97SIGMAR1 | |
| SCHEMBL10884643 | 0.94 | AHCY (0.59) | AHCYDOT1LHIF1ATMEM97SIGMAR1 | |
| SCHEMBL10883817 | 0.92 | AHCY (0.66) | AHCYDOT1LHIF1ATMEM97SIGMAR1 | |
| SCHEMBL10887386 | 0.88 | ADORA2A (0.52) | AHCYDOT1LADORA2AADORA2B | |
| SCHEMBL10885276 | 0.88 | ADORA2A (0.52) | AHCYDOT1LADORA2AADORA2B | |
| SCHEMBL11059822 | 0.87 | TRDMT1 (0.57) | AHCYDOT1LHIF1ATMEM97SIGMAR1 | |
| SCHEMBL11054733 | 0.87 | AHCY (0.68) | AHCYDOT1LHIF1ATMEM97SIGMAR1 | |
| SCHEMBL10896379 | 0.86 | AHCY (0.54) | AHCYDOT1LHIF1AHSP90B1 | |
| SCHEMBL11197673 | 0.85 | AHCY (0.57) | AHCYDOT1LHIF1ATMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071926-B1 | NEW RIBOFURANURONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-08 | — | — | EP | disclosed |
| US-4479942-A | Tetrahydrofurnancarboxylic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-30 | — | — | US | disclosed |
| EP-0071926-A1 | New ribofuranuronic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-02-16 | — | — | EP | disclosed |