Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 14/20 | 0.44 |
| ▸ | TYMP | P19971 | 4/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10964068 | 0.80 | GPR84 (0.44) | GPR84TYMPHCAR2 | |
| SCHEMBL10885262 | 0.73 | GPR84 (0.42) | GPR84TYMPHCAR2 | |
| SCHEMBL30968704 | 0.72 | TYMP (0.51) | GPR84TYMPHCAR2 | |
| SCHEMBL14524977 | 0.71 | TYMP (0.48) | GPR84TYMPHCAR2 | |
| SCHEMBL10197626 | 0.65 | GPR84 (0.38) | GPR84TYMP | |
| SCHEMBL22579524 | 0.65 | KDM4E (0.33) | GPR84TYMP | |
| SCHEMBL25344146 | 0.64 | TYMP (0.46) | TYMP | |
| Tetrabuthylammonium SCHEMBL1284221 | 0.63 | SLC22A1 (0.60) | GPR84TYMP | |
| SCHEMBL891089 | 0.63 | TYMP (0.46) | GPR84TYMP | |
| Palmitic Acid SCHEMBL31098101 | 0.61 | GPR84 (0.71) | GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065165-B1 | 5-OXYMETHYL-4-ACYL-1,3-DIHYDRO-2H-IMIDAZOL-2-ONES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-06-18 | — | — | EP | disclosed |
| EP-0065165-A1 | 5-Oxymethyl-4-acyl-1,3-dihydro-2H-imidazol-2-ones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1982-11-24 | — | — | EP | disclosed |