Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 11/20 | 0.42 |
| ▸ | TYMP | P19971 | 4/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | UNG | P13051 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10885266 | 0.73 | GPR84 (0.44) | GPR84TYMPHCAR2 | |
| SCHEMBL10964068 | 0.73 | GPR84 (0.44) | GPR84TYMPHCAR2KMT2AUNG | |
| SCHEMBL29674655 | 0.69 | TYMP (0.51) | GPR84TYMPHCAR2 | |
| SCHEMBL14524977 | 0.68 | TYMP (0.48) | GPR84TYMPHCAR2KMT2A | |
| SCHEMBL18825085 | 0.67 | HIF1A (0.41) | GPR84TYMPHIF1AEPAS1KMT2A | |
| SCHEMBL9766749 | 0.66 | HIF1A (0.44) | GPR84HIF1AEPAS1HCAR2KMT2A | |
| SCHEMBL11057529 | 0.64 | HIF1A (0.50) | GPR84HIF1AEPAS1HCAR2KMT2A | |
| SCHEMBL9736947 | 0.64 | HIF1A (0.39) | GPR84TYMPHIF1AEPAS1 | |
| SCHEMBL9766716 | 0.64 | HIF1A (0.46) | GPR84HIF1AEPAS1HCAR2KMT2A | |
| SCHEMBL11201746 | 0.64 | TSHR (0.38) | TYMPHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065165-B1 | 5-OXYMETHYL-4-ACYL-1,3-DIHYDRO-2H-IMIDAZOL-2-ONES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-06-18 | — | — | EP | disclosed |
| EP-0065165-A1 | 5-Oxymethyl-4-acyl-1,3-dihydro-2H-imidazol-2-ones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1982-11-24 | — | — | EP | disclosed |