Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.60 |
| ▸ | AHCY | P23526 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.55 |
| ▸ | PRKACA | P17612 | 2/20 | 0.54 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.54 |
| ▸ | NSD2 | O96028 | 2/20 | 0.53 |
| ▸ | PCMT1 | P22061 | 2/20 | 0.53 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.53 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.53 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.53 |
| ▸ | TRDMT1 | O14717 | 1/20 | 0.53 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.53 |
| ▸ | RNMT | O43148 | 1/20 | 0.53 |
| ▸ | INMT | O95050 | 1/20 | 0.53 |
| ▸ | TPMT | P51580 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10886080 | 0.90 | AHCY (0.62) | NNMTAHCYHIF1ATMEM97SIGMAR1 | |
| SCHEMBL10887652 | 0.88 | AHCY (0.55) | NNMTAHCYHIF1ATMEM97SIGMAR1 | |
| SCHEMBL11059806 | 0.85 | ATM (0.59) | AHCYHIF1ATMEM97SIGMAR1ADORA2A | |
| SCHEMBL10886589 | 0.85 | AHCY (0.67) | AHCYHIF1ATMEM97SIGMAR1ADORA2A | |
| SCHEMBL10889028 | 0.85 | NPEPPS (0.64) | AHCYHIF1ATMEM97SIGMAR1ADORA2A | |
| SCHEMBL11203369 | 0.85 | NPEPPS (0.64) | AHCYHIF1ATMEM97SIGMAR1ADORA2A | |
| SCHEMBL10883740 | 0.85 | NPEPPS (0.64) | AHCYHIF1ATMEM97SIGMAR1ADORA2A | |
| SCHEMBL10884983 | 0.84 | DOT1L (0.59) | AHCYHIF1ATMEM97SIGMAR1ADORA2A | |
| SCHEMBL11204220 | 0.83 | DOT1L (0.58) | AHCYHIF1ATMEM97SIGMAR1ADORA2A | |
| SCHEMBL10885975 | 0.83 | DOT1L (0.58) | AHCYHIF1ATMEM97SIGMAR1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071926-B1 | NEW RIBOFURANURONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-08 | — | — | EP | disclosed |
| US-4479942-A | Tetrahydrofurnancarboxylic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-30 | — | — | US | disclosed |