SCHEMBL10885342

SCHEMBL10885342

CC1=CC=C2C(=Cc3ccccc32)C1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 4/20 0.44
CDC25A P30304 3/20 0.44
MAPT P10636 6/20 0.41
IDO1 P14902 5/20 0.41
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
ALDH1A1 P00352 4/20 0.41
LMNA P02545 4/20 0.41
HPGD P15428 3/20 0.41
MAPK1 P28482 3/20 0.41
BLM P54132 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
PKM P14618 2/20 0.41
PLIN1 O60240 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2C9 P11712 2/20 0.41
MAOA P21397 2/20 0.41
CYP2C19 P33261 2/20 0.41
PLIN5 Q00G26 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1480880 0.82 CDC25B (0.42) CDC25BCDC25AMAPTIDO1MEN1
SCHEMBL28278858 0.81 MEN1 (0.41) CDC25BCDC25AMAPTIDO1MEN1
SCHEMBL18143566 0.79 CDC25B (0.42) CDC25BCDC25AMAPTIDO1MEN1
SCHEMBL28679867 0.79 MAOA (0.40) MAOAMAOBACHEELANE
SCHEMBL8896914 0.79 MAOA (0.44) MAPTMAOAGAAMAOBELANE
SCHEMBL1882102 0.78 NSD2 (0.41) CDC25BCDC25AMAPTIDO1MEN1
SCHEMBL978806 0.78 BACE1 (0.48) CDC25BCDC25AMAPTIDO1MEN1
SCHEMBL827619 0.78 PTPRC (0.41) CDC25BCDC25AMAPTIDO1MEN1
SCHEMBL2518069 0.78 MAPT (0.41) CDC25BCDC25AMAPTIDO1MEN1
SCHEMBL9810978 0.78 CDC25B (0.41) CDC25BCDC25AMAPTIDO1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104003903-B The synthetic method of sartanbiphenyl QIDONG DONGYUE PHARMACY CO., LTD. (CN) 2016-05-25 CN claimed
CN-101418269-B Streptomycete and application thereof in reduction of aromatic ketone UNIV DALIAN TECH 2010-12-01 CN claimed
CN-101418269-A Streptomycete and application thereof in reduction of aromatic ketone UNIV DALIAN TECH (CN) 2009-04-29 CN claimed
CN-113652705-B Method for synthesizing fluorenone through catalytic electrolysis of N-hydroxyphthalimide 北京工业大学 2022-07-22 CN disclosed
CN-110023274-B Method for producing fluorenylidene diallylphenols and fluorenylidene diallylphenols 杰富意化学株式会社 2022-05-13 CN disclosed
CN-113652705-A Method for synthesizing fluorenone by catalyzing and electrolyzing N-hydroxyphthalimide 北京工业大学 2021-11-16 CN disclosed
US-10906855-B2 Method for producing fluorenylidene diallylphenols, and fluorenylidene diallylphenols JFE CHEMICAL CORPORATION (JP) 2021-02-02 US disclosed
US-20200190001-A1 METHOD FOR PRODUCING FLUORENYLIDENE DIALLYLPHENOLS, AND FLUORENYLIDENE DIALLYLPHENOLS JFE CHEMICAL CORPORATION (JP) 2020-06-18 US disclosed
CN-110023274-A The manufacturing method and fluorenylidene diallyl phenols of fluorenylidene diallyl phenols 杰富意化学株式会社 2019-07-16 CN disclosed
CN-104003903-B The synthetic method of sartanbiphenyl QIDONG DONGYUE PHARMACY CO., LTD. (CN) 2016-05-25 CN disclosed
CN-104003903-A Synthetic method of 2-cyano-4'-methylbiphenyl Qidong dongyue pharmaceutical co ltd 2014-08-27 CN disclosed
CN-101418269-B Streptomycete and application thereof in reduction of aromatic ketone UNIV DALIAN TECH 2010-12-01 CN disclosed
CN-101418269-A Streptomycete and application thereof in reduction of aromatic ketone UNIV DALIAN TECH (CN) 2009-04-29 CN disclosed
EP-0005379-B2 PHOTOSENSITIVE COMPOSITIONS CONTAINING CARBONYLIC HALIDES AS ACTIVATORS Dynachem Corporation (US) 1986-06-04 EP disclosed
US-4552830-A UNSATURATED COMPOUND, FREE RADICAL-PRODUCING PHOTOINITIATOR FLUORA COLOR FORMER, PROTON DONOR DYNACHEM CORPORATION (US) 1985-11-12 US disclosed
US-4343885-A PHOTORESISTS DYNACHEM CORPORATION (US) 1982-08-10 US disclosed
EP-0005380-B1 PHOTOTROPIC PHOTOSENSITIVE COMPOSITIONS CONTAINING A FLUORAN COLORFORMER Dynachem Corporation (US) 1982-01-06 EP disclosed
EP-0005379-B1 PHOTOSENSITIVE COMPOSITIONS CONTAINING CARBONYLIC HALIDES AS ACTIVATORS Dynachem Corporation (US) 1981-12-23 EP disclosed
EP-0005380-A2 Phototropic photosensitive compositions containing a fluoran colorformer Dynachem Corporation (US) 1979-11-14 EP disclosed
EP-0005379-A2 Photosensitive compositions containing carbonylic halides as activators Dynachem Corporation (US) 1979-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10906855-B2 Method for producing fluorenylidene diallylphenols, and fluorenylidene diallylphenols AKR7A2, GSTP1, CYP4F2 CDC25B 2141/4885CDC25A 3217/4885MAPT 4221/4885
US-20200190001-A1 METHOD FOR PRODUCING FLUORENYLIDENE DIALLYLPHENOLS, AND FLUORENYLIDENE DIALLYLPHENOLS AKR7A2, GSTP1, CYP4F2 CDC25B 2141/4885CDC25A 3217/4885MAPT 4221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.