SCHEMBL1882102

SCHEMBL1882102

NC1=CC=C2C(=Cc3ccccc32)C1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 4/20 0.41
PTPN1 P18031 3/20 0.41
HKDC1 Q2TB90 1/20 0.41
CDC25B P30305 3/20 0.41
CDC25A P30304 1/20 0.41
SLC2A1 P11166 1/20 0.38
MAOA P21397 2/20 0.35
ADORA2A P29274 2/20 0.35
FGR P09769 1/20 0.35
PIM1 P11309 1/20 0.35
CSNK1A1 P48729 1/20 0.35
CSNK1D P48730 1/20 0.35
DYRK1A Q13627 1/20 0.35
HIPK2 Q9H2X6 1/20 0.35
CSNK1G1 Q9HCP0 1/20 0.35
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
PTPRC P08575 6/20 0.34
ALDH1A1 P00352 4/20 0.34
POLB P06746 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18143566 0.79 CDC25B (0.42) PTPN1CDC25BCDC25AMAOAMEN1
SCHEMBL1032694 0.79 NPC1 (0.39) NSD2MEN1KMT2APTPRCALDH1A1
SCHEMBL9019022 0.79 NPC1 (0.39) NSD2MEN1KMT2APTPRCALDH1A1
SCHEMBL2518069 0.78 MAPT (0.41) PTPN1CDC25BCDC25AMAOAMEN1
SCHEMBL827619 0.78 PTPRC (0.41) NSD2PTPN1CDC25BCDC25AMAOA
SCHEMBL8909770 0.78 CDC25B (0.41) PTPN1CDC25BCDC25AMAOAMEN1
SCHEMBL9810978 0.78 CDC25B (0.41) PTPN1CDC25BCDC25AMAOAMEN1
SCHEMBL978806 0.78 BACE1 (0.48) PTPN1HKDC1CDC25BCDC25AMAOA
SCHEMBL10885342 0.78 CDC25B (0.44) NSD2PTPN1HKDC1CDC25BCDC25A
SCHEMBL7442079 0.78 CDC25B (0.41) PTPN1CDC25BCDC25AMAOAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117756619-A 3-bromofluorenone and preparation method thereof 维思普新材料(苏州)有限公司 2024-03-26 CN claimed
CN-1105944-C Method of obtaining a lift-off imaged pattern CLARIENT INTERNAT CORP (CH) 2003-04-16 CN claimed
CN-1221497-A Metal ion reduction of aminochromatic chromophores and their use in synthesis of low metal bottom anti-reflective coatings for photoresists CLARYANT INTERNATIONAL CO LTD (CH) 1999-06-30 CN claimed
CN-1181820-A Method of obtaining a lift-off imaged pattern CLARIENT INTERMATIONAL CORP (CH) 1998-05-13 CN claimed
EP-0410287-B1 Polyphosphazene derivatives containing carbonyl groups and variously alkylated tertiary amino groups CONSIGLIO NAZIONALE RICERCHE (IT) 1995-11-02 EP claimed
EP-0430434-B1 Process for the preparation of fluoroaromatic and fluoroheteroaromatic compounds ZENECA LTD (GB) 1994-09-14 EP claimed
EP-0430434-A2 Process for the preparation of fluoroaromatic and fluoroheteroaromatic compounds ZENECA LIMITED (GB) 1991-06-05 EP claimed
EP-0410287-A2 Polyphosphazene derivatives containing carbonyl groups and variously alkylated tertiary amino groups CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 1991-01-30 EP claimed
JP-62059934-A None JP disclosed
CN-117756619-B 3-Bromofluorenone and preparation method thereof 维思普新材料(苏州)有限公司 2026-01-06 CN disclosed
CN-117756619-A 3-bromofluorenone and preparation method thereof 维思普新材料(苏州)有限公司 2024-03-26 CN disclosed
CN-117756619-A 3-bromofluorenone and preparation method thereof 维思普新材料(苏州)有限公司 2024-03-26 CN disclosed
CN-102167756-B Hyperbranched polymer and method for producing the same NISSAN CHEMICAL IND LTD 2012-12-26 CN disclosed
CN-102167757-B Hyperbranched polymer and method for producing the same NISSAN CHEMICAL IND LTD 2012-12-26 CN disclosed
US-4540700-A Treatment of diabetic complications with certain spiro-imidazolidine-diones ALCON LABORATORIES, INC. (US) 1985-09-10 US disclosed
EP-0128333-A2 Agent for inactivating the mutagenicity of coffee and method therefor SUNTORY LIMITED (JP) 1984-12-19 EP disclosed
EP-0124891-A2 Antimutagenic agent and method of inactivating the mutagenicity of foods and beverages by using said agent SUNTORY LIMITED (JP) 1984-11-14 EP disclosed
US-4436745-A TETRACYCLIC SPIROHYDANTOINS ALCON LABORATORIES, INC. (US) 1984-03-13 US disclosed
WO-1983003543-A1 METHOD OF INHIBITING ALDOSE REDUCTASE ACTIVITY, COMPOSITIONS THEREFOR AND PROCESS FOR PREPARING SPIRO-FLUOROFLUOREN AND SPIRO-DIFLUOROFLUOREN COMPOUNDS ALCON LAB INC (US) 1983-10-27 WO disclosed
EP-0092385-A2 Hydantoin derivatives for use in inhibiting aldose reductase activity, compositions therefor and process for preparing spiro-fluoren compounds ALCON LABORATORIES, INC. (US) 1983-10-26 EP disclosed