Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | PPOX | P50336 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10886245 | 0.92 | TDP1 (0.41) | TDP1MERTKMEN1KMT2ATTR | |
| SCHEMBL10885337 | 0.85 | TDP1 (0.43) | TDP1MERTKMEN1KMT2ATTR | |
| SCHEMBL10885953 | 0.81 | TDP1 (0.48) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10889127 | 0.80 | TDP1 (0.48) | TDP1MERTKMEN1KMT2ATTR | |
| SCHEMBL10887601 | 0.79 | TDP1 (0.42) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10886929 | 0.79 | TDP1 (0.44) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10903805 | 0.78 | TDP1 (0.42) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10883652 | 0.78 | TDP1 (0.45) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10888370 | 0.78 | TDP1 (0.41) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10884682 | 0.78 | SIRT5 (0.46) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126294-B1 | NEW DIPHENYL ETHERS HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1986-11-20 | — | — | EP | disclosed |
| US-4609753-A | PRE- AND POSTEMERGENCE | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1986-09-02 | — | — | US | disclosed |
| EP-0126294-A1 | New diphenyl ethers having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1984-11-28 | — | — | EP | disclosed |