Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | PPOX | P50336 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10884127 | 0.90 | TDP1 (0.45) | TDP1MAPTPKMLMNAMERTK | |
| SCHEMBL10885462 | 0.85 | TDP1 (0.41) | TDP1MAPTPKMLMNAMERTK | |
| SCHEMBL10883652 | 0.85 | TDP1 (0.45) | TDP1MAPTPKMLMNAMEN1 | |
| SCHEMBL10884682 | 0.85 | SIRT5 (0.46) | TDP1MAPTPKMLMNAMEN1 | |
| SCHEMBL10888234 | 0.85 | TDP1 (0.46) | TDP1MAPTPKMLMNAMEN1 | |
| SCHEMBL10886267 | 0.83 | TDP1 (0.45) | TDP1MAPTPKMLMNAMEN1 | |
| SCHEMBL10886889 | 0.83 | ALDH1A1 (0.44) | TDP1MAPTPKMLMNAMEN1 | |
| SCHEMBL10888230 | 0.81 | TDP1 (0.41) | TDP1MAPTPKMLMNAMEN1 | |
| SCHEMBL10888131 | 0.81 | TDP1 (0.42) | TDP1MAPTPKMLMNAMEN1 | |
| SCHEMBL8693937 | 0.80 | MEN1 (0.57) | TDP1MAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126294-B1 | NEW DIPHENYL ETHERS HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1986-11-20 | — | — | EP | disclosed |
| US-4609753-A | PRE- AND POSTEMERGENCE | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1986-09-02 | — | — | US | disclosed |
| EP-0126294-A1 | New diphenyl ethers having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1984-11-28 | — | — | EP | disclosed |