Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.78 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.69 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.59 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.59 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL118026 | 0.88 | KDR (1.00) | KDRPDK1GRM4TRPV1CA1 | |
| SCHEMBL29364392 | 0.88 | KDR (1.00) | KDRPDK1GRM4TRPV1CA1 | |
| SCHEMBL9835641 | 0.86 | KDR (0.78) | KDRPDK1GRM4TRPV1NPSR1 | |
| SCHEMBL11787916 | 0.86 | KDR (0.58) | KDRPDK1GRM4TRPV1NPSR1 | |
| SCHEMBL2329430 | 0.86 | KDR (0.78) | KDRPDK1GRM4TRPV1NPSR1 | |
| SCHEMBL31495074 | 0.85 | KDR (0.76) | KDRPDK1GRM4TRPV1NPSR1 | |
| Fluoride SCHEMBL11788392 | 0.85 | KDR (0.76) | KDRPDK1GRM4TRPV1NPSR1 | |
| SCHEMBL29759440 | 0.85 | KDR (0.76) | KDRPDK1GRM4TRPV1NPSR1 | |
| SCHEMBL2457115 | 0.85 | KDR (0.76) | KDRPDK1GRM4TRPV1NPSR1 | |
| SCHEMBL462753 | 0.85 | KDR (0.76) | KDRPDK1GRM4TRPV1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129214-B1 | METHOD FOR THE PREPARATION OF BENZENAMINES | OCCIDENTAL CHEMICAL CORPORATION (US) | 1986-10-29 | — | — | EP | claimed |
| EP-0129214-A1 | Method for the preparation of benzenamines | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-12-27 | — | — | EP | claimed |
| US-4481370-A | REACTING HYDROGEN FLUORIDE WITH A PHENYL CARBAMIC FLUORIDE | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-11-06 | — | — | US | claimed |
| EP-0129214-B1 | METHOD FOR THE PREPARATION OF BENZENAMINES | OCCIDENTAL CHEMICAL CORPORATION (US) | 1986-10-29 | — | — | EP | disclosed |
| US-4481370-A | REACTING HYDROGEN FLUORIDE WITH A PHENYL CARBAMIC FLUORIDE | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-11-06 | — | — | US | disclosed |
| US-3983172-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-09-28 | — | — | US | disclosed |