Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.76 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.68 |
| ▸ | CNR2 | P34972 | 1/20 | 0.61 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.58 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.58 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3645017 | 0.89 | KDR (0.73) | KDRPDK1CNR2GRM4TRPV1 | |
| SCHEMBL1291336 | 0.87 | KDR (0.71) | KDRPDK1CNR2GRM4TRPV1 | |
| SCHEMBL29625148 | 0.87 | KDR (0.71) | KDRPDK1CNR2GRM4TRPV1 | |
| SCHEMBL29625146 | 0.87 | KDR (0.71) | KDRPDK1CNR2GRM4TRPV1 | |
| SCHEMBL118026 | 0.86 | KDR (1.00) | KDRPDK1GRM4TRPV1CA1 | |
| SCHEMBL29364392 | 0.86 | KDR (1.00) | KDRPDK1GRM4TRPV1CA1 | |
| SCHEMBL8407112 | 0.86 | KDR (0.69) | KDRPDK1CNR2GRM4TRPV1 | |
| SCHEMBL8409965 | 0.86 | KDR (0.69) | KDRPDK1CNR2GRM4TRPV1 | |
| SCHEMBL9835641 | 0.85 | KDR (0.78) | KDRPDK1CNR2GRM4TRPV1 | |
| SCHEMBL2329430 | 0.85 | KDR (0.78) | KDRPDK1CNR2GRM4TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025037871-A1 | TRICYCLIC COMPOUND AND USE THEREOF AS MAT2A INHIBITOR | 에스케이바이오팜 주식회사 | 2025-02-20 | — | — | WO | disclosed |