Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10885684 | 0.81 | ESR1 (0.44) | PPARGSRD5A2AKR1B1NR3C1ALDH1A1 | |
| SCHEMBL10885689 | 0.74 | CTNNB1 (0.38) | PPARGSRD5A2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL6241535 | 0.71 | CARM1 (0.56) | SRD5A2AKR1B1NR3C1CARM1PRMT6 | |
| SCHEMBL10603325 | 0.71 | NCEH1 (0.42) | PPARGPPARANCEH1PLA2G1B | |
| SCHEMBL3316494 | 0.68 | KDM4E (0.41) | PPARGNCEH1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL6235731 | 0.67 | SRD5A2 (0.64) | PPARGSRD5A2PPARAAKR1B1NR3C1 | |
| SCHEMBL1145770 | 0.66 | SRD5A2 (0.83) | SRD5A2AKR1B1NR3C1PTGS1 | |
| SCHEMBL8641931 | 0.66 | SRD5A2 (0.58) | SRD5A2AKR1B1NR3C1ALDH1A1HPGD | |
| SCHEMBL2172254 | 0.65 | AKR1B1 (0.43) | SRD5A2AKR1B1PTGS1AKR1C3AKR1C2 | |
| SCHEMBL6237474 | 0.65 | SRD5A2 (0.50) | SRD5A2AKR1B1NR3C1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0032286-B1 | METHOD FOR ANALYSIS FOR A MEMBER OF AN IMMUNOLOGICAL PAIR USING A TEST SURFACE; KIT AND TEST SURFACE MATERIAL THEREFOR | SYVA COMPANY (US) | 1986-01-08 | — | — | EP | disclosed |