SCHEMBL3316494

SCHEMBL3316494

CCCc1c(O)cc2ccccc2c1C(N)=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.41
ALDH1A1 P00352 4/20 0.41
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
HPGD P15428 3/20 0.41
CYP1A2 P05177 1/20 0.41
GLA P06280 1/20 0.41
CYP2C19 P33261 1/20 0.41
HSD17B10 Q99714 1/20 0.41
NCEH1 Q6PIU2 1/20 0.40
TRPM4 Q8TD43 1/20 0.40
GAA P10253 4/20 0.39
GPR84 Q9NQS5 1/20 0.38
ME2 P23368 1/20 0.37
ME1 P48163 1/20 0.37
ME3 Q16798 1/20 0.37
POLB P06746 2/20 0.37
ALOX15 P16050 1/20 0.37
GPR35 Q9HC97 1/20 0.37
LDHA P00338 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3315873 0.89 MAPT (0.45) KDM4EALDH1A1HPGDGLAHSD17B10
SCHEMBL3316307 0.89 MAPT (0.45) KDM4EALDH1A1HPGDGLAHSD17B10
SCHEMBL3312529 0.89 MAPT (0.45) KDM4EALDH1A1HPGDGLAHSD17B10
SCHEMBL11225617 0.79 TRPM4 (0.48) KDM4EALDH1A1MEN1KMT2AHPGD
SCHEMBL3454685 0.77 KDM4E (0.52) KDM4EALDH1A1MEN1KMT2AHPGD
SCHEMBL15090920 0.77 ALDH1A1 (0.44) KDM4EALDH1A1MEN1KMT2AHPGD
SCHEMBL10818026 0.74 ATM (0.43) NCEH1GPR84EGFRSRC
SCHEMBL5968378 0.73 MAPT (0.46) KDM4EALDH1A1MEN1KMT2AHPGD
SCHEMBL11045803 0.73 CYP1A2 (0.61) KDM4EALDH1A1MEN1KMT2AHPGD
SCHEMBL5749296 0.73 ALDH1A1 (0.65) KDM4EALDH1A1MEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8445651-B2 Method for producing charge control agent and toner HUBEI DINGLONG CHEMICAL CO., LTD. (CN) 2013-05-21 US disclosed
US-20100105884-A1 METHOD FOR PRODUCING CHARGE CONTROL AGENT AND TONER HUBEI DINGLONG CHEMICAL CO., LTD. (CN) 2010-04-29 US disclosed