Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156731 | 0.88 | CASP1 (0.60) | CTRB1ALDH1A1CYP1A2CTSLCTSS | |
| SCHEMBL6955527 | 0.88 | CASP1 (0.60) | CTRB1ALDH1A1CYP1A2CTSLCTSS | |
| SCHEMBL6156740 | 0.88 | CASP1 (0.60) | CTRB1ALDH1A1CYP1A2CTSLCTSS | |
| SCHEMBL10885690 | 0.86 | CTRB1 (0.51) | CTRB1ALDH1A1CYP1A2CTSLCTSS | |
| SCHEMBL7285800 | 0.86 | ATM (0.55) | CTRB1ALDH1A1CYP1A2CTSLCTSS | |
| SCHEMBL10979333 | 0.85 | CTRB1 (0.54) | CTRB1ALDH1A1CYP1A2CTSLCTSS | |
| SCHEMBL16201457 | 0.84 | ATM (0.54) | CTRB1ALDH1A1CYP1A2CTSLCTSS | |
| SCHEMBL6958944 | 0.84 | ATM (0.54) | CTRB1ALDH1A1CYP1A2CTSLCTSS | |
| SCHEMBL7134978 | 0.84 | CTRB1 (0.55) | CTRB1ALDH1A1CYP1A2CTSLCTSS | |
| SCHEMBL4998172 | 0.84 | CTRB1 (0.55) | CTRB1ALDH1A1CYP1A2CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071926-B1 | NEW RIBOFURANURONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-08 | — | — | EP | disclosed |
| US-4479942-A | Tetrahydrofurnancarboxylic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-30 | — | — | US | disclosed |
| EP-0071926-A1 | New ribofuranuronic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-02-16 | — | — | EP | disclosed |