SCHEMBL10887231

SCHEMBL10887231

[CH2]CCC(OCCC)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 2/20 0.38
SLC6A4 P31645 3/20 0.37
HTT P42858 2/20 0.37
LMNA P02545 5/20 0.36
CYP1A2 P05177 4/20 0.36
CYP2D6 P10635 4/20 0.36
SCN1A P35498 3/20 0.36
SCN2A Q99250 3/20 0.36
SCN3A Q9NY46 3/20 0.36
TSHR P16473 3/20 0.36
OPRM1 P35372 3/20 0.36
OPRK1 P41145 3/20 0.36
CHRM1 P11229 2/20 0.36
ADRA2B P18089 2/20 0.36
SLC6A2 P23975 2/20 0.36
HTR2A P28223 2/20 0.36
HTR2C P28335 2/20 0.36
HRH1 P35367 2/20 0.36
DRD3 P35462 2/20 0.36
THPO P40225 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6538486 0.87 NPC1 (0.41) LMNATSHRHTR2AKCNH2SMN1; SMN2
SCHEMBL8567639 0.85 SLC6A4 (0.39) SLC6A4HTTLMNACYP1A2CYP2D6
SCHEMBL28042231 0.82 SLC7A5 (0.41) AOC3LMNAOPRM1OPRK1HTR2A
SCHEMBL2167004 0.81 CASR (0.36) AOC3SLC6A4HTTLMNACYP1A2
SCHEMBL4871158 0.81 LMNA (0.43) AOC3SLC6A4HTTLMNACYP1A2
SCHEMBL28042425 0.81 HTR2A (0.41) LMNAOPRM1OPRK1HTR2AKCNH2
SCHEMBL6538968 0.80 LTA4H (0.39) LMNATSHRHTR2AKCNH2MAPK1
SCHEMBL2165677 0.80 CASR (0.36) AOC3SLC6A4HTTLMNACYP1A2
SCHEMBL11247546 0.79 HTT (0.35) AOC3SLC6A4HTTLMNACYP1A2
SCHEMBL24925628 0.78 GSR (0.47) AOC3SLC6A4HTTLMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4598155-A 3(5-tetrazolyl)1,4-diaminoanthraquinones CIBA-GEIGY CORPORATION (US) 1986-07-01 US disclosed
EP-0079862-B1 1,4-DIAMINO-ANTHRAQUINONE COMPOUNDS CIBA-GEIGY AG (CH) 1986-01-15 EP disclosed
EP-0079862-A2 1,4-Diamino-anthraquinone compounds CIBA-GEIGY AG (CH) 1983-05-25 EP disclosed