Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | CES1 | P23141 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.52 |
| ▸ | FEN1 | P39748 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10886619 | 0.92 | KMT2A (0.64) | HPGDKMT2AMEN1CYP3A4MAPK1 | |
| SCHEMBL10916871 | 0.82 | MAPT (0.52) | HPGDKMT2AMEN1CYP3A4MAPK1 | |
| SCHEMBL1977011 | 0.81 | KMT2A (0.80) | HPGDKMT2AMEN1CYP3A4MAPK1 | |
| SCHEMBL10647153 | 0.80 | HDAC1 (0.53) | HPGDKMT2AMEN1CYP3A4MAPK1 | |
| SCHEMBL10888944 | 0.79 | KMT2A (0.76) | HPGDKMT2AMEN1CYP3A4MAPK1 | |
| Dibenzoylmethane SCHEMBL30179786 | 0.79 | MEN1 (0.94) | HPGDKMT2AMEN1CYP3A4MAPK1 | |
| Dibenzoylmethane SCHEMBL28167353 | 0.79 | MEN1 (0.94) | HPGDKMT2AMEN1CYP3A4MAPK1 | |
| SCHEMBL9622162 | 0.79 | MAPT (0.53) | HPGDKMT2AMEN1CYP3A4MAPK1 | |
| SCHEMBL10885494 | 0.77 | MAPT (0.59) | HPGDKMT2AMEN1CYP3A4MAPK1 | |
| Dibenzoylmethane SCHEMBL1704711 | 0.76 | MEN1 (1.00) | HPGDKMT2AMEN1CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046161-B1 | STABILIZED POLYVINYLHALIDE RESIN | PHOENIX CHEMICAL CORPORATION (US) | 1986-11-12 | — | — | EP | disclosed |
| US-4371651-A | PHOTOSTABILITY, HEAT RESISTANCE | PHOENIX CHEMICAL CORPORATION (US) | 1983-02-01 | — | — | US | disclosed |
| EP-0046161-A2 | Stabilized Polyvinylhalide resin | PHOENIX CHEMICAL CORPORATION (US) | 1982-02-24 | — | — | EP | disclosed |