Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 5/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.48 |
| ▸ | CES1 | P23141 | 7/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28437029 | 0.89 | MAPT (0.58) | MAPTCYP2C9GMNNTP53POLB | |
| SCHEMBL14998165 | 0.89 | MAPT (0.58) | MAPTCYP2C9GMNNTP53POLB | |
| SCHEMBL6465332 | 0.89 | MAPT (0.58) | MAPTCYP2C9GMNNTP53POLB | |
| SCHEMBL15457916 | 0.89 | MAPT (0.58) | MAPTCYP2C9GMNNTP53POLB | |
| SCHEMBL9185052 | 0.88 | CES1 (0.48) | MAPTNAAACES2PLA2G4BCES1 | |
| SCHEMBL2522380 | 0.87 | ALDH1A1 (0.58) | MAPTCYP2C9GMNNTP53POLB | |
| SCHEMBL10647153 | 0.83 | HDAC1 (0.53) | MAPTCYP2C9PLA2G4BCES1CYP3A4 | |
| SCHEMBL8756244 | 0.82 | ALDH1A1 (0.59) | MAPTCYP2C9GMNNTP53POLB | |
| SCHEMBL10886619 | 0.82 | KMT2A (0.64) | MAPTCYP2C9CES1CYP3A4HPGD | |
| SCHEMBL3357504 | 0.81 | L3MBTL1 (0.55) | MAPTCYP2C9GMNNTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307358-B1 | 1,3-DIKETONES CONTAINING ETHERS OR THIOETHERS AND THEIR USE AS STABILISING AGENTS IN CHLORINATED POLYMERS | CIBA-GEIGY AG (CH) | 1992-02-12 | — | — | EP | disclosed |
| US-4992504-A | Heat resistance, photostability | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| EP-0307358-A1 | 1,3-Diketones containing ethers or thioethers and their use as stabilising agents in chlorinated polymers | CIBA-GEIGY AG (CH) | 1989-03-15 | — | — | EP | disclosed |