Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.47 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10647153 | 0.90 | HDAC1 (0.53) | MAPTSMN1; SMN2CYP3A4HPGDMAPK1 | |
| SCHEMBL10886619 | 0.86 | KMT2A (0.64) | MAPTSMN1; SMN2CYP3A4HPGDMAPK1 | |
| SCHEMBL10885494 | 0.82 | MAPT (0.59) | MAPTSMN1; SMN2CYP3A4HPGDMAPK1 | |
| SCHEMBL10887258 | 0.82 | HPGD (0.59) | MAPTSMN1; SMN2CYP3A4HPGDMAPK1 | |
| SCHEMBL9622162 | 0.80 | MAPT (0.53) | MAPTSMN1; SMN2CYP3A4HPGDMAPK1 | |
| SCHEMBL6563638 | 0.78 | ALDH1A1 (0.74) | MAPTSMN1; SMN2CYP3A4HPGDMAPK1 | |
| SCHEMBL10918605 | 0.77 | HDAC1 (0.46) | MAPTSMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL7900079 | 0.76 | CYP2C19 (0.53) | MAPTSMN1; SMN2MAPK1KMT2ATDP1 | |
| SCHEMBL9622180 | 0.75 | CYP2C19 (0.62) | MAPTSMN1; SMN2CYP3A4HPGDMAPK1 | |
| SCHEMBL1977011 | 0.75 | KMT2A (0.80) | MAPTSMN1; SMN2CYP3A4HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0138349-B1 | 3-BENZOYL-2-MERCAPTOPROPIONIC ACID DERIVATIES | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1986-11-12 | — | — | EP | disclosed |
| US-4594197-A | 3-benzoyl-2-mercaptopropionic acid derivatives | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1986-06-10 | — | — | US | disclosed |
| EP-0138349-A1 | 3-Benzoyl-2-mercaptopropionic acid derivaties | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1985-04-24 | — | — | EP | disclosed |