SCHEMBL108874

SCHEMBL108874

CCc1ncc(C)nc1C

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
JAK3 P52333 1/20 0.35
KDM5B Q9UGL1 2/20 0.33
S1PR4 O95977 1/20 0.31
PDE10A Q9Y233 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29666109 1.00 JAK3 (0.35) JAK3KDM5BS1PR4PDE10AKDM4E
SCHEMBL29350484 0.92 JAK3 (0.32) JAK3KDM5BS1PR4KDM4EALDH1A1
SCHEMBL15272101 0.90 JAK3 (0.31) JAK3
SCHEMBL29832120 0.83 KDM4E (0.35) KDM5BS1PR4PDE10AKDM4EALDH1A1
SCHEMBL756047 0.83 KDM4E (0.35) KDM5BS1PR4PDE10AKDM4EALDH1A1
SCHEMBL16431031 0.82 SPR (0.30)
Pyrazine SCHEMBL28235706 0.82
SCHEMBL7156533 0.82 HSP90AA1 (0.36) JAK3PDE10AKDM4EALDH1A1
SCHEMBL29364752 0.82 HSP90AA1 (0.36) JAK3PDE10AKDM4EALDH1A1
SCHEMBL28250244 0.81 S1PR4 (0.31) S1PR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2229 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12628862-B2 Liquid tobacco extract, method for making and aerosol-generating articles comprising such PHILIP MORRIS PRODUCTS S.A. (CH) 2026-05-19 US claimed
US-20260114475-A1 ANIMAL FOOD COMPOSITIONS WITH IMPROVED PALATABILITY AND CUSTOMIZABILITY, AND METHODS FOR PREPARING THE SAME MARS, INCORPORATED (US) 2026-04-30 US claimed
EP-4731020-A1 LOW SUGAR-BASED FOOD COMPOSITIONS WITH ROASTED INGREDIENT Société des Produits Nestlé S.A. (CH) 2026-04-29 EP claimed
US-20260096574-A1 CHOCOLATE REPLICAS PRODUCED FROM INDIVIDUAL COMPONENTS VOYAGE FOODS INC (US) 2026-04-09 US claimed
US-20260096585-A1 ORAL COMPOSITION KAO CORPORATION (JP) 2026-04-09 US claimed
EP-4369947-B1 FLAVOR ENHANCER FOR PROVIDING ROASTED CHICKEN FLAVOR GIVAUDAN SA (CH) 2026-04-01 EP claimed
EP-4704596-A1 METHODS AND COMPOSITION FOR PALATABLE PET FOODS Société des Produits Nestlé S.A. (CH) 2026-03-11 EP claimed
US-12568998-B2 Flavouring composition with balanced taste profile SYMRISE AG (DE) 2026-03-10 US claimed
US-20260007144-A1 CHOCOLATE REPLICAS PRODUCED FROM INDIVIDUAL COMPONENTS VOYAGE FOODS INC (US) 2026-01-08 US claimed
EP-4672982-A1 PROCESS FOR PREPARING A FLAVOR COMPOSITION Firmenich SA (CH) 2026-01-07 EP claimed
US-6083419-A FOR SEMICONDUCTORS CABOT CORPORATION (US) 2000-07-04 US claimed
EP-1006813-A1 USE OF 1-NONEN-3-ONE AS A FLAVOURING AGENT SOCIETE DES PRODUITS NESTLE S.A. (CH) 2000-06-14 EP claimed
EP-0896042-A1 A polishing composition including an inhibitor of tungsten etching Cabot Corporation (US) 1999-02-10 EP claimed
WO-1999005706-A1 A POLISHING COMPOSITION INCLUDING AN INHIBITOR OF TUNGSTEN ETCHING CABOT CORPORATION (US) 1999-02-04 WO claimed
WO-1998005220-A1 USE OF 1-NONEN-3-ONE AS A FLAVOURING AGENT SOCIETE DES PRODUITS NESTLE S.A. (CH) 1998-02-12 WO claimed
EP-0413368-B1 Bread aroma, production thereof, and use of the same for the aromatisation of foodstuffs and delicacies THURN & TAXIS BRAUEREI (DE) 1994-08-17 EP claimed
EP-0413368-A1 Bread aroma, production thereof, and use of the same for the aromatisation of foodstuffs and delicacies FÜRSTLICHE BRAUEREI THURN UND TAXIS REGENSBURG GMBH (DE) 1991-02-20 EP claimed
US-4179526-A 2-((METHYLTHIO)METHYL)-3-PHENYL-2-PROPENAL INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-12-18 US claimed
US-4156029-A Alpha-substituted alkylidene methionals and uses thereof in foodstuffs and flavors for foodstuffs INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1979-05-22 US claimed
US-4064279-A Alpha-substituted alkylidene methionals and uses thereof in foodstuffs and flavors for foodstuffs INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-12-20 US claimed