SCHEMBL756047

SCHEMBL756047

CCc1ncc(C)nc1CC

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.35
ALDH1A1 P00352 2/20 0.35
S1PR4 O95977 1/20 0.35
GAA P10253 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
KDM5B Q9UGL1 1/20 0.34
PDCD1 Q15116 1/20 0.34
CD274 Q9NZQ7 1/20 0.34
TSHR P16473 1/20 0.33
ATM Q13315 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
USP2 O75604 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PDE10A Q9Y233 1/20 0.31
MAPKAPK2 P49137 2/20 0.31
MEN1 O00255 1/20 0.31
TP53 P04637 1/20 0.31
KMT2A Q03164 1/20 0.31
CRHR1 P34998 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29832120 1.00 KDM4E (0.35) KDM4EALDH1A1S1PR4GAATDP1
SCHEMBL108874 0.83 JAK3 (0.35) KDM4EALDH1A1S1PR4KDM5BPDE10A
SCHEMBL160005 0.83 KDM4E (0.34) KDM4EALDH1A1S1PR4GAATDP1
SCHEMBL29364954 0.83 KDM4E (0.34) KDM4EALDH1A1S1PR4GAATDP1
SCHEMBL29666109 0.83 JAK3 (0.35) KDM4EALDH1A1S1PR4KDM5BPDE10A
SCHEMBL29350484 0.81 JAK3 (0.32) KDM4EALDH1A1S1PR4KDM5B
Pyrazine SCHEMBL28235706 0.80
SCHEMBL17583174 0.79 S1PR4 (0.33) KDM4EALDH1A1S1PR4KDM5BTSHR
SCHEMBL10924648 0.79 S1PR4 (0.39) KDM4EALDH1A1S1PR4KDM5BPDCD1
SCHEMBL10394906 0.79 MAPKAPK2 (0.44) TSHRMAPKAPK2DHFRNOS3NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1420 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12628862-B2 Liquid tobacco extract, method for making and aerosol-generating articles comprising such PHILIP MORRIS PRODUCTS S.A. (CH) 2026-05-19 US claimed
US-20260096574-A1 CHOCOLATE REPLICAS PRODUCED FROM INDIVIDUAL COMPONENTS VOYAGE FOODS INC (US) 2026-04-09 US claimed
US-12568998-B2 Flavouring composition with balanced taste profile SYMRISE AG (DE) 2026-03-10 US claimed
US-20260026543-A1 TOBACCO FLAVOURED DRY POWDER FORMULATION PHILIP MORRIS PRODUCTS SA (CH) 2026-01-29 US claimed
US-20260007144-A1 CHOCOLATE REPLICAS PRODUCED FROM INDIVIDUAL COMPONENTS VOYAGE FOODS INC (US) 2026-01-08 US claimed
EP-4672967-A2 ALTERNATIVE COFFEE BEVERAGES Compound Foods Inc. (US) 2026-01-07 EP claimed
EP-4672982-A1 PROCESS FOR PREPARING A FLAVOR COMPOSITION Firmenich SA (CH) 2026-01-07 EP claimed
WO-2025226566-A1 INSTANT WHITE COFFEE STARBUCKS CORPORATION (US) 2025-10-30 WO claimed
WO-2025226563-A1 METHODS FOR PRODUCING INSTANT WHITE COFFEE STARBUCKS CORPORATION (US) 2025-10-30 WO claimed
US-20250324997-A1 Methods for Producing Instant White Coffee STARBUCKS CORPORATION 2025-10-23 US claimed
CN-1161034-C Use of 1-nonen-3-ones as flavoring agents �Ʒ� 2004-08-11 CN claimed
EP-0731648-B1 FLAVOURING COMPOSITIONS AND METHOD FIRMENICH & CIE (CH) 2003-03-26 EP claimed
US-6296889-B1 Use of 1-nonen-3-one for aroma/flavor enhancement NESTEC S.A. (CH) 2001-10-02 US claimed
US-6287620-B1 Flavor enhancing methods FIRMENICH SA (CH) 2001-09-11 US claimed
EP-1006813-A1 USE OF 1-NONEN-3-ONE AS A FLAVOURING AGENT SOCIETE DES PRODUITS NESTLE S.A. (CH) 2000-06-14 EP claimed
CN-1231581-A Use of 1-nonen-3-ones as flavoring agents NESTLE SA (CH) 1999-10-13 CN claimed
US-5939568-A Accelerated catalysis of olefinic epoxidations THE SCRIPPS RESEARCH INSTITUTE (US) 1999-08-17 US claimed
WO-1998033786-A9 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS 1998-12-30 WO claimed
WO-1998033786-A1 ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS THE SCRIPPS RESEARCH INSTITUTE (US) 1998-08-06 WO claimed
WO-1998005220-A1 USE OF 1-NONEN-3-ONE AS A FLAVOURING AGENT SOCIETE DES PRODUITS NESTLE S.A. (CH) 1998-02-12 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12568998-B2 Flavouring composition with balanced taste profile TAS2R20, TAS2R50, TAS2R40 KDM4E 4345/4885ALDH1A1 1337/4885S1PR4 1662/4885
US-20260007144-A1 CHOCOLATE REPLICAS PRODUCED FROM INDIVIDUAL COMPONENTS HAAO, PTGES2, PTGES KDM4E 331/4885ALDH1A1 74/4885S1PR4 2041/4885
US-12628862-B2 Liquid tobacco extract, method for making and aerosol-generating articles comprising such NDUFB10, EXOSC10, NDUFB7 KDM4E 2813/4885ALDH1A1 990/4885S1PR4 4155/4885
US-20260026543-A1 TOBACCO FLAVOURED DRY POWDER FORMULATION CTNND1, IL17A, TAS2R20 KDM4E 3168/4885ALDH1A1 726/4885S1PR4 3506/4885
US-20260096574-A1 CHOCOLATE REPLICAS PRODUCED FROM INDIVIDUAL COMPONENTS HAAO, HTR6, SCD KDM4E 95/4885ALDH1A1 492/4885S1PR4 2681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.