Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 3/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.32 |
| ▸ | TEK | Q02763 | 3/20 | 0.32 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | FRK | P42685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11095461 | 0.89 | MAPK14 (0.47) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL7084894 | 0.81 | MAPK14 (0.47) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL10846339 | 0.80 | KDM5B (0.32) | — | |
| SCHEMBL10887823 | 0.74 | LMNA (0.41) | LMNANSD3FAAHMAPK13MAPK12 | |
| SCHEMBL10847804 | 0.71 | LMNA (0.35) | LMNANSD3FAAHMAPTL3MBTL1 | |
| SCHEMBL11175120 | 0.70 | MAPK14 (0.59) | MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL9370596 | 0.67 | LMNA (0.43) | LMNANSD3FAAHMAPK13MAPK12 | |
| SCHEMBL20466312 | 0.66 | MAPK14 (0.60) | LMNANSD3FAAHMAPK13MAPK12 | |
| SCHEMBL11083061 | 0.64 | MAPK14 (0.52) | MAPK13MAPK12MAPK11MAPK14PTGS2 | |
| SCHEMBL9257885 | 0.64 | MEN1 (0.55) | LMNAMAPTL3MBTL1TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4576958-A | VASODILATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-03-18 | — | — | US | disclosed |