Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | ACE | P12821 | 3/20 | 0.59 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.57 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.57 |
| ▸ | ITGAL | P20701 | 3/20 | 0.57 |
| ▸ | ECE1 | P42892 | 4/20 | 0.56 |
| ▸ | NMBR | P28336 | 2/20 | 0.56 |
| ▸ | FPR2 | P25090 | 1/20 | 0.55 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28836525 | 1.00 | ALOX15 (0.64) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL29908071 | 1.00 | ALOX15 (0.64) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL28836524 | 1.00 | ALOX15 (0.64) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL732867 | 0.89 | ALOX15 (0.59) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL11370918 | 0.85 | ALOX15 (0.67) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL11370921 | 0.85 | ALOX15 (0.67) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL1285921 | 0.84 | NMBR (0.76) | ALOX15ACEECE1NMBR | |
| SCHEMBL3808330 | 0.84 | NMBR (0.76) | ALOX15ACEECE1NMBR | |
| SCHEMBL29386277 | 0.84 | NMBR (0.76) | ALOX15ACEECE1NMBR | |
| SCHEMBL29935468 | 0.84 | NMBR (0.76) | ALOX15ACEECE1NMBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0109044-B1 | PENEMS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, PROCESS FOR PREPARING THEM | SCHERING CORPORATION (US) | 1986-10-15 | — | — | EP | disclosed |
| US-4540580-A | 2-[(1'R)-1'-Aminoalkyl]penems | SCHERING CORPORATION (US) | 1985-09-10 | — | — | US | disclosed |
| EP-0109044-A1 | Penems, pharmaceutical compositions containing them, process for preparing them | SCHERING CORPORATION (US) | 1984-05-23 | — | — | EP | disclosed |