Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11001574 | 0.90 | KMT2A (0.62) | KMT2AMEN1ALDH1A1CYP1A1CYP19A1 | |
| SCHEMBL11003320 | 0.81 | KMT2A (0.60) | KMT2AMEN1ALDH1A1CYP1A1CYP19A1 | |
| SCHEMBL28054792 | 0.80 | KMT2A (0.53) | KMT2AMEN1ALDH1A1CYP19A1NPSR1 | |
| SCHEMBL10888469 | 0.79 | CYP19A1 (0.50) | CYP1A1CYP19A1CYP2C9CYP2C19EPHX2 | |
| SCHEMBL838159 | 0.79 | LMNA (0.42) | KMT2AMEN1ALDH1A1HTTLMNA | |
| SCHEMBL6321049 | 0.74 | KMT2A (0.57) | KMT2AMEN1ALDH1A1CYP19A1NPSR1 | |
| SCHEMBL10999688 | 0.74 | KMT2A (0.48) | KMT2AMEN1ALDH1A1CYP19A1NPSR1 | |
| SCHEMBL27575719 | 0.74 | KMT2A (0.48) | KMT2AMEN1ALDH1A1CYP19A1HTT | |
| SCHEMBL10999691 | 0.74 | KMT2A (0.48) | KMT2AMEN1ALDH1A1CYP19A1NPSR1 | |
| SCHEMBL10891262 | 0.73 | CYP19A1 (0.53) | KMT2AMEN1ALDH1A1CYP19A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4628104-A | ANTIANAEROBIC AGENTS | G. D. SEARLE & CO. (US) | 1986-12-09 | — | — | US | disclosed |