Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | IDH1 | O75874 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11001574 | 0.87 | KMT2A (0.62) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL28282814 | 0.85 | KMT2A (0.49) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL27602500 | 0.85 | CYP19A1 (0.55) | KMT2AMEN1ALDH1A1LMNACYP19A1 | |
| SCHEMBL27575719 | 0.84 | KMT2A (0.48) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL10888136 | 0.80 | KMT2A (0.53) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL10959984 | 0.80 | CYP19A1 (0.56) | KMT2AMEN1ALDH1A1LMNAHTT | |
| SCHEMBL27775612 | 0.80 | CYP1A2 (0.42) | KMT2AMEN1ALDH1A1CYP19A1 | |
| SCHEMBL7815542 | 0.79 | CYP19A1 (0.51) | KMT2AMEN1ALDH1A1LMNACYP19A1 | |
| SCHEMBL7815541 | 0.79 | CYP19A1 (0.51) | KMT2AMEN1ALDH1A1LMNACYP19A1 | |
| SCHEMBL7783933 | 0.79 | TSHR (0.58) | KMT2AMEN1ALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105367564-A | N-[4-phenyl-5-(1,2,4-triazole-1-yl)thiazole-2-yl]amide and preparation and application thereof | UNIV HUNAN | 2016-03-02 | — | — | CN | claimed |
| CN-105367564-B | N [base of 4 phenyl 5 (base of 1,2,4 triazole 1) thiazole 2] acid amides and its preparation and application | 湖南大学 | 2018-03-23 | — | — | CN | disclosed |
| CN-105367564-A | N-[4-phenyl-5-(1,2,4-triazole-1-yl)thiazole-2-yl]amide and preparation and application thereof | UNIV HUNAN | 2016-03-02 | — | — | CN | disclosed |