Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL724866 | 0.80 | CHRNA7 (0.74) | CHRNA7CYP2A6TDP1L3MBTL1HRH1 | |
| SCHEMBL29485692 | 0.80 | CHRNA7 (0.74) | CHRNA7CYP2A6TDP1L3MBTL1HRH1 | |
| SCHEMBL348856 | 0.80 | CHRNA7 (0.57) | CHRNA7CYP2A6TDP1L3MBTL1HRH1 | |
| SCHEMBL868537 | 0.80 | CHRNA7 (0.57) | CHRNA7CYP2A6TDP1L3MBTL1HRH1 | |
| SCHEMBL8507218 | 0.80 | CHRNA7 (0.57) | CHRNA7CYP2A6TDP1L3MBTL1HRH1 | |
| SCHEMBL7241565 | 0.80 | CHRNA7 (0.57) | CHRNA7CYP2A6TDP1L3MBTL1HRH1 | |
| SCHEMBL6157916 | 0.80 | CHRNA7 (0.57) | CHRNA7CYP2A6TDP1L3MBTL1HRH1 | |
| SCHEMBL10888485 | 0.80 | CHRNA7 (0.57) | CHRNA7CYP2A6TDP1L3MBTL1HRH1 | |
| Bromide SCHEMBL17353587 | 0.78 | CHRNA7 (0.55) | CHRNA7CYP2A6TDP1L3MBTL1HRH1 | |
| Hydrochloric Acid SCHEMBL28122048 | 0.78 | CHRNA7 (0.55) | CHRNA7CYP2A6TDP1L3MBTL1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4616015-A | HYPOTENSIVE AGENT, ANTULCER AGENT, ANTICOAGULANT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-07 | — | — | US | disclosed |
| EP-0122627-A2 | Triazine derivatives, processes for preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-24 | — | — | EP | disclosed |