Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL868537 | 0.98 | CHRNA7 (0.57) | CHRNA7CYP2A6TDP1L3MBTL1HRH1 | |
| Hydrochloric Acid SCHEMBL28122048 | 0.96 | CHRNA7 (0.55) | CHRNA7CYP2A6TDP1L3MBTL1HRH1 | |
| SCHEMBL11329185 | 0.87 | CYP2A6 (0.59) | CHRNA7CYP2A6TDP1L3MBTL1HRH1 | |
| SCHEMBL8199625 | 0.85 | TDP1 (0.61) | CHRNA7CYP2A6TDP1L3MBTL1HRH1 | |
| SCHEMBL2050612 | 0.82 | — | — | |
| SCHEMBL724866 | 0.79 | CHRNA7 (0.74) | CHRNA7CYP2A6TDP1L3MBTL1HRH1 | |
| SCHEMBL29485692 | 0.79 | CHRNA7 (0.74) | CHRNA7CYP2A6TDP1L3MBTL1HRH1 | |
| SCHEMBL2690999 | 0.79 | CHRNA7 (0.45) | CHRNA7CYP2A6TDP1L3MBTL1HRH1 | |
| SCHEMBL348856 | 0.78 | CHRNA7 (0.57) | CHRNA7CYP2A6TDP1L3MBTL1HRH1 | |
| SCHEMBL6157916 | 0.78 | CHRNA7 (0.57) | CHRNA7CYP2A6TDP1L3MBTL1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11394069-B2 | Additives for a flow battery | BROMINE COMPOUNDS LTD. (IL) | 2022-07-19 | — | — | US | disclosed |
| US-20180323484-A1 | ADDITIVES FOR A FLOW BATTERY | BROMINE COMPOUNDS LTD. (IL) | 2018-11-08 | — | — | US | disclosed |
| US-9722281-B2 | Processes for preparing 1-alkyl-3-alkyl-pyridinium bromide and uses thereof as additives in electrochemical cells | BROMINE COMPOUNDS LTD. (IL) | 2017-08-01 | — | — | US | disclosed |
| WO-2017081678-A1 | ADDITIVES FOR A FLOW BATTERY | BROMINE COMPOUNDS LTD. (IL) | 2017-05-18 | — | — | WO | disclosed |
| EP-2953930-B1 | PROCESSES FOR PREPARING 1-ALKYL-3-ALKYL-PYRIDINIUM BROMIDE AND USES THEREOF AS ADDITIVES IN ELECTROCHEMICAL CELLS | BROMINE COMPOUNDS LTD (IL) | 2016-12-07 | — | — | EP | disclosed |
| US-20150372351-A1 | PROCESSES FOR PREPARING L-ALKYL-3-ALKYL-PYRIDINIUM BROMIDE AND USES THEREOF AS ADDITIVES IN ELECTROCHEMICAL CELLS | BROMINE COMPOUNDS LTD. (IL) | 2015-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150372351-A1 | PROCESSES FOR PREPARING L-ALKYL-3-ALKYL-PYRIDINIUM BROMIDE AND USES THEREOF AS ADDITIVES IN ELECTROCHEMICAL CELLS | PLP2, PLPBP, AZI2 | CHRNA7 286/4885CYP2A6 1722/4885TDP1 1298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.