Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 9/20 | 0.66 |
| ▸ | ABCB1 | P08183 | 10/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10889496 | 1.00 | ABCC9 (0.66) | ABCC9ABCB1 | |
| SCHEMBL10889492 | 1.00 | ABCC9 (0.66) | ABCC9ABCB1 | |
| Water SCHEMBL9710826 | 0.88 | ABCB1 (0.65) | ABCC9ABCB1 | |
| SCHEMBL10847997 | 0.86 | ABCB1 (0.56) | ABCC9ABCB1 | |
| SCHEMBL10847989 | 0.86 | ABCB1 (0.56) | ABCC9ABCB1 | |
| Acetaldehyde SCHEMBL9397673 | 0.85 | ABCC9 (0.64) | ABCC9ABCB1 | |
| Formamide SCHEMBL9398663 | 0.85 | ABCC9 (0.64) | ABCC9ABCB1 | |
| SCHEMBL9193340 | 0.84 | ABCC9 (0.59) | ABCC9ABCB1 | |
| SCHEMBL9193344 | 0.84 | ABCC9 (0.59) | ABCC9ABCB1 | |
| SCHEMBL9193352 | 0.84 | ABCC9 (0.59) | ABCC9ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0095316-B1 | PHARMACEUTICALLY ACTIVE AMINOBENZOPYRANS | BEECHAM GROUP PLC (GB) | 1986-12-03 | — | — | EP | disclosed |
| US-4568692-A | LOWERING BLOOD PRESSURE | BEECHAM GROUP P.L.C. | 1986-02-04 | — | — | US | disclosed |
| US-4481214-A | 4-Acylaminobenzopyrans useful as anti-hypertensive agents | BEECHAM GROUP P.L.C. (GB) | 1984-11-06 | — | — | US | disclosed |
| EP-0095316-A1 | Pharmaceutically active aminobenzopyrans | BEECHAM GROUP PLC (GB) | 1983-11-30 | — | — | EP | disclosed |