Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 9/20 | 0.56 |
| ▸ | ABCC9 | O60706 | 9/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10847997 | 1.00 | ABCB1 (0.56) | ABCB1ABCC9KDM4E | |
| SCHEMBL10889492 | 0.86 | ABCC9 (0.66) | ABCB1ABCC9 | |
| SCHEMBL10889481 | 0.86 | ABCC9 (0.66) | ABCB1ABCC9 | |
| SCHEMBL10889496 | 0.86 | ABCC9 (0.66) | ABCB1ABCC9 | |
| SCHEMBL10847995 | 0.82 | ABCC9 (0.50) | ABCB1ABCC9 | |
| SCHEMBL10853875 | 0.82 | ABCC9 (0.50) | ABCB1ABCC9 | |
| SCHEMBL10853889 | 0.82 | ABCC9 (0.50) | ABCB1ABCC9 | |
| SCHEMBL10851952 | 0.81 | ABCC9 (0.39) | ABCC9 | |
| SCHEMBL10851967 | 0.81 | ABCC9 (0.39) | ABCC9 | |
| SCHEMBL10848203 | 0.81 | AKR1B1 (0.38) | ABCB1ABCC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4629734-A | HYPOTENSIVE AGENTS | BEECHAM GROUP P.L.C. (GB) | 1986-12-16 | — | — | US | claimed |
| EP-0126350-A1 | Novel compounds | BEECHAM GROUP PLC (GB) | 1984-11-28 | — | — | EP | claimed |