Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.50 |
| ▸ | PPARA | Q07869 | 4/20 | 0.50 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10892107 | 0.97 | ALDH1A1 (0.47) | PPARGPPARAPPARDIGF2BP2ALDH1A1 | |
| SCHEMBL10887691 | 0.89 | IGF2BP2 (0.51) | PPARGPPARAPPARDIGF2BP2MAPT | |
| SCHEMBL10885570 | 0.85 | ALDH1A1 (0.57) | ALDH1A1NPSR1TAS1R3TAS1R1SOAT1 | |
| SCHEMBL11133780 | 0.85 | NPSR1 (0.56) | ALDH1A1LMNAMEN1MAPTALOX12 | |
| SCHEMBL10890006 | 0.84 | PPARG (0.57) | PPARGPPARAPPARDNPSR1 | |
| SCHEMBL6364308 | 0.84 | PPARA (0.62) | PPARGPPARAPPARDIGF2BP2MEN1 | |
| SCHEMBL9784540 | 0.81 | LMNA (0.53) | PPARGPPARAPPARDALDH1A1LMNA | |
| SCHEMBL10889567 | 0.81 | LMNA (0.53) | PPARGPPARAPPARDALDH1A1LMNA | |
| SCHEMBL10888068 | 0.81 | CNR1 (0.53) | PPARGPPARAPPARDNPSR1 | |
| SCHEMBL10891269 | 0.80 | CA12 (0.57) | ALDH1A1LMNAMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4623662-A | ANTICHOLESTEROL, ANTILIPEMIC | AMERICAN CYANAMID COMPANY (US) | 1986-11-18 | — | — | US | disclosed |