Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 13/20 | 0.36 |
| ▸ | ESR1 | P03372 | 12/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10873981 | 0.86 | ESR2 (0.34) | ESR2ESR1HSD17B1CYP3A4TSHR | |
| SCHEMBL10893644 | 0.81 | HTR2A (0.40) | ESR2ESR1CYP3A4TSHRRECQL | |
| SCHEMBL11731334 | 0.74 | CYP3A4 (0.41) | ESR2ESR1CYP3A4TSHRRECQL | |
| SCHEMBL9694900 | 0.73 | ESR2 (0.37) | ESR2ESR1HSD17B1CYP3A4RECQL | |
| SCHEMBL16499910 | 0.72 | TSHR (0.37) | ESR2ESR1CYP3A4TSHRRECQL | |
| SCHEMBL10936237 | 0.71 | CA2 (0.41) | ESR2ESR1CYP3A4TSHRRECQL | |
| SCHEMBL1928567 | 0.69 | ESR2 (0.48) | ESR2ESR1HSD17B1CYP3A4TSHR | |
| SCHEMBL12042083 | 0.69 | LMNA (0.41) | ESR2ESR1HSD17B1RECQL | |
| SCHEMBL31490395 | 0.68 | CYP3A4 (0.42) | ESR2ESR1HSD17B1CYP3A4TSHR | |
| SCHEMBL1128366 | 0.68 | CYP3A4 (0.42) | ESR2ESR1HSD17B1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4581350-A | O-(perfluoroalkylthiophenyl) (thio or amido) phosphates as pesticides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1986-04-08 | — | — | US | disclosed |
| EP-0127049-A2 | Organic phosphoric-acid esters | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1984-12-05 | — | — | EP | disclosed |